Literature DB >> 24995236

Efficacy of postoperative prophylactic antibiotic therapy in third molar surgery.

Rohit S1, Praveen Reddy B2.   

Abstract

INTRODUCTION: Surgical extraction of mandibular third molar is the most frequently performed procedure in oral surgery. This procedure is associated with significant postoperative sequelae such as trismus, swelling, pain and infection. The need of antibiotic therapy during the removal of mandibular third molar has been a contentious issue.
METHOD: This study investigated a regimen by using amoxycillin and metronidazole in one group and without using antibiotics in the other. Both the groups were assessed postoperatively on the 1(st), 2(nd), 5(th), 7(th) and 10(th) days by the same observer for post operative mouth opening (interincisal distance), presence of a purulent discharge at the site of surgery, pain and swelling. RESULT: Overall, no statistically significant difference was seen between both the treatment groups when interincisal distance, pain, swelling and purulent discharge were considered.
CONCLUSION: The results of this study failed to show any advantage which was associated with the routine postoperative use of antibiotics in asymptomatic third molar surgeries.

Entities:  

Keywords:  Antibiotics; Dental; Pain; Swelling; Trismus

Year:  2014        PMID: 24995236      PMCID: PMC4080057          DOI: 10.7860/JCDR/2014/7441.4325

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  12 in total

1.  Antibiotic prophylaxis and third molar surgery.

Authors:  M V Martin; A N Kanatas; P Hardy
Journal:  Br Dent J       Date:  2005-03-26       Impact factor: 1.626

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Authors:  D T Falconer; E E Roberts
Journal:  Br J Oral Maxillofac Surg       Date:  1992-06       Impact factor: 1.651

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Authors:  L J Peterson
Journal:  J Oral Maxillofac Surg       Date:  1990-06       Impact factor: 1.895

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Authors:  D A Mitchell
Journal:  Br Dent J       Date:  1986-04-19       Impact factor: 1.626

5.  An assessment of the use of prophylactic antibiotics in third molar surgery.

Authors:  J B Curran; S Kennett; A R Young
Journal:  Int J Oral Surg       Date:  1974

6.  Single-dose and multi-dose clindamycin therapy fails to demonstrate efficacy in preventing infectious and inflammatory complications in third molar surgery.

Authors:  T Kaczmarzyk; J Wichlinski; J Stypulkowska; M Zaleska; M Panas; J Woron
Journal:  Int J Oral Maxillofac Surg       Date:  2007-04-03       Impact factor: 2.789

7.  Role of antimicrobials in third molar surgery: prospective, double blind,randomized, placebo-controlled clinical study.

Authors:  C H Sekhar; V Narayanan; M F Baig
Journal:  Br J Oral Maxillofac Surg       Date:  2001-04       Impact factor: 1.651

8.  Metronidazole (Flagyl) and Arnica Montana in the prevention of post-surgical complications, a comparative placebo controlled clinical trial.

Authors:  G S Kaziro
Journal:  Br J Oral Maxillofac Surg       Date:  1984-02       Impact factor: 1.651

9.  Metronidazole: two or three times daily--a comparative controlled clinical trial of the efficacy of two different dosing schedules of metronidazole for chemoprophylaxis following third molar surgery.

Authors:  C J Lloyd; P D Earl
Journal:  Br J Oral Maxillofac Surg       Date:  1994-06       Impact factor: 1.651

10.  Postoperative prophylactic antibiotic treatment in third molar surgery--a necessity?

Authors:  Paul W Poeschl; Doris Eckel; Ellen Poeschl
Journal:  J Oral Maxillofac Surg       Date:  2004-01       Impact factor: 1.895

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  6 in total

1.  Benefits of not Prescribing Prophylactic Antibiotics After Third Molar Surgery.

Authors:  Anchal Prajapati; Aalap Prajapati; Swati Sathaye
Journal:  J Maxillofac Oral Surg       Date:  2015-07-05

2.  Evaluation of Infection and Effective Factors in Impacted Mandibular Third Molar Surgeries: A Cross-Sectional Study.

Authors:  Farrokh Farhadi; Parya Emamverdizadeh; Mahdi Hadilou; Parisa Jalali
Journal:  Int J Dent       Date:  2022-05-04

3.  Comparative Efficacy of Different Oral Doses of Clindamycin in Preventing Post-Operative Sequelae of Lower Third Molar Surgery-A Randomized, Triple-Blind Study.

Authors:  Anna Janas-Naze; Gaja Torbicka; Damian Chybicki; Małgorzata Lipczyńska-Lewandowska; Wei Zhang
Journal:  Medicina (Kaunas)       Date:  2022-05-17       Impact factor: 2.948

Review 4.  Infection, Alveolar Osteitis, and Adverse Effects Using Metronidazole in Healthy Patients Undergoing Third Molar Surgery: A Meta-analysis.

Authors:  Mario Alberto Isiordia-Espinoza; Othoniel H Aragon-Martinez; Ronell E Bollogna-Molina; Ángel J Alonso-Castro
Journal:  J Maxillofac Oral Surg       Date:  2017-07-01

Review 5.  Efficacy of amoxicillin and amoxicillin/clavulanic acid in the prevention of infection and dry socket after third molar extraction. A systematic review and meta-analysis.

Authors:  M-I Arteagoitia; L Barbier; J Santamaría; G Santamaría; E Ramos
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2016-07-01

6.  Efficacy of Submucosal Injection of Chymotrypsin, Oral Serratiopeptidase or Oral Dexamethasone in Reducing Postoperative Complications Following Impacted Lower Third Molar Surgery: A Prospective, Randomized, Double-Blind, Controlled Clinical Trial.

Authors:  Essam Ahmed Al-Moraissi; Elham Aziz Al-Zendani; Abeer Mohammed Al-Selwi
Journal:  Front Oral Health       Date:  2020-12-08
  6 in total

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