Literature DB >> 24995194

Antibiotic prescribing in various clinical departments in a tertiary care teaching hospital in northern India.

Kumar Abhijit1, Pushpawati Jain2, Prerna Upadhyaya3, Shipra Jain4.   

Abstract

BACKGROUND: Antibiotic resistance is not only a problem for the individual patient; it also reduces the effectiveness of established treatment and has become a major threat to public health by increasing the complexity and cost of treatment and reducing the probability of a successful outcome. AIM: A prospective cross sectional study was carried out with the aim of identifying prescription pattern of antibiotics in a tertiary care teaching hospital in Northern India.
MATERIALS AND METHODS: A total of 300 prescriptions were collected, collated and analysed from the indoor patients of MG hospital, Jaipur, India from the department of Medicine, Surgery and Orthopaedics. The prescribing and dispensing details of antibiotics from each prescription were recorded in the tabular form as mentioned in Data Acquisition form. Comparison of antibiotic prescribing practices among all the three departments was made by using Percentage method.
RESULTS: Majority of prescriptions (51%) with single drug was prescribed in Medicine department, followed by 16% in surgery and only 2% in Orthopaedics. Prescriptions with 3 drugs were prescribed mostly in Orthopaedics (66%) followed by 46% in Surgery and 10% in Medicine. 51% prescriptions in Orthopaedics department were of Ceftriaxone+ Sulbactam+ Amikacin. Thirty four percent prescriptions in Medicine department were of Ceftriaxone. 18% prescriptions in Surgery department were of Ceftriaxone+ Sulbactam+ Tobramycin.
CONCLUSION: This study clearly highlights the practice of Poly-Pharmacy and injudicious usage of antibiotics in hospital settings. The Government of India is planning to revise the antibiotic policy issued in 2011 and put a ban on over the counter availability of third generation antibiotics. General public awareness and sensitization of doctors and revision of clinical drug policy is the need of the hour to bring the changes at all possible level for the longterm and better clinical outcome in medical practice.

Entities:  

Keywords:  Antibiotic resistance; Prescription monitoring; Rational use of medicines

Year:  2014        PMID: 24995194      PMCID: PMC4080015          DOI: 10.7860/JCDR/2014/8637.4384

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  9 in total

1.  Use of antibiotics in hospitals in south-western France.

Authors:  A M Rogues; B Placet-Thomazeau; P Parneix; I Vincent; M C Ploy; N Marty; B Merillou; J C Labadie; J P Gachie
Journal:  J Hosp Infect       Date:  2004-11       Impact factor: 3.926

2.  Pattern of prescribing practices in the Madhya Pradesh, India.

Authors:  S S Bhartiy; M Shinde; S Nandeshwar; S C Tiwari
Journal:  Kathmandu Univ Med J (KUMJ)       Date:  2008 Jan-Mar

3.  Antimicrobial resistance. Is a major threat to public health.

Authors:  R Wise; T Hart; O Cars; M Streulens; R Helmuth; P Huovinen; M Sprenger
Journal:  BMJ       Date:  1998-09-05

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Authors:  H R Patterson
Journal:  J R Coll Gen Pract       Date:  1986-05

Review 5.  Bridging the gap between clinical pharmacology and rational drug prescribing.

Authors:  L E Ramsay
Journal:  Br J Clin Pharmacol       Date:  1993-06       Impact factor: 4.335

6.  Prescribing patterns in medical outpatients.

Authors:  P Ravi Shankar; P Partha; S Nagesh
Journal:  Int J Clin Pract       Date:  2002-09       Impact factor: 2.503

7.  Comparison of different methods to estimate prevalence of drug use by using pharmacy records.

Authors:  A K Mantel-Teeuwisse; O H Klungel; W M Verschuren; A Porsius; A de Boer
Journal:  J Clin Epidemiol       Date:  2001-11       Impact factor: 6.437

8.  Utilization pattern of antibiotics in different wards of specialized Sari Emam University Hospital in Iran.

Authors:  Mohammad Ali Ebrahimzadeh; Mohammad Shokrzadeh; Ahmad Ramezani
Journal:  Pak J Biol Sci       Date:  2008-01-15

Review 9.  Interventions to improve antibiotic prescribing practices for hospital inpatients.

Authors:  P Davey; E Brown; L Fenelon; R Finch; I Gould; G Hartman; A Holmes; C Ramsay; E Taylor; M Wilcox; P Wiffen
Journal:  Cochrane Database Syst Rev       Date:  2005-10-19
  9 in total
  1 in total

1.  Compliance with the 4Ds of antimicrobial stewardship practice in a tertiary care centre.

Authors:  Diksha Dixit; Rajat Ranka; Prasan Kumar Panda
Journal:  JAC Antimicrob Resist       Date:  2021-09-15
  1 in total

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