Literature DB >> 24994748

Posterior spinal artery aneurysm rupture after 'Ecstasy' abuse.

Jeremiah Johnson1, Shnehal Patel2, Efrat Saraf-Lavi3, Mohammad Ali Aziz-Sultan4, Dileep R Yavagal5.   

Abstract

Posterior spinal artery (PSA) aneurysms are a rare cause of subarachnoid hemorrhage (SAH). The commonly abused street drug 3,4-methylenedioxymethamphetamine (MDMA) or 'Ecstasy' has been linked to both systemic and neurological complications. A teenager presented with neck stiffness, headaches and nausea after ingesting 'Ecstasy'. A brain CT was negative for SAH but a CT angiogram suggested cerebral vasculitis. A lumbar puncture showed SAH but a cerebral angiogram was negative. After a spinal MR angiogram identified abnormalities on the dorsal surface of the cervical spinal cord, a spinal angiogram demonstrated a left PSA 2 mm fusiform aneurysm. The patient underwent surgery and the aneurysmal portion of the PSA was excised without postoperative neurological sequelae. 'Ecstasy' can lead to neurovascular inflammation, intracranial hemorrhage, SAH and potentially even de novo aneurysm formation and subsequent rupture. PSA aneurysms may be treated by endovascular proximal vessel occlusion or open surgical excision. 2014 BMJ Publishing Group Ltd.

Entities:  

Keywords:  Aneurysm; Drug; Inflammation; Spinal cord; Spine

Mesh:

Substances:

Year:  2014        PMID: 24994748      PMCID: PMC4091472          DOI: 10.1136/bcr-2014-011248

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  16 in total

1.  Dissecting aneurysm of the thoracic posterior spinal artery. Case illustration.

Authors:  Andrew N Nemecek; Gill Sviri; Robert Hevner; Bhasavaraj Ghodke; Gavin W Britz
Journal:  J Neurosurg Spine       Date:  2006-12

2.  Aneurysms of spinal arteries associated with intramedullary arteriovenous malformations. II. Results of AVM endovascular treatment and hemodynamic considerations.

Authors:  A Biondi; J J Merland; J E Hodes; A Aymard; D Reizine
Journal:  AJNR Am J Neuroradiol       Date:  1992 May-Jun       Impact factor: 3.825

3.  Ruptured aneurysm of the posterior spinal artery of the upper cervical spinal cord: case report.

Authors:  Y Goto; Y Kamijyo; Y Yonekawa; H Kikuchi
Journal:  Neurosurgery       Date:  1988-03       Impact factor: 4.654

4.  3 cases of primary intracranial hemorrhage associated with "Molly", a purified form of 3,4-methylenedioxymethamphetamine (MDMA).

Authors:  D Ethan Kahn; Nicholas Ferraro; Ronald J Benveniste
Journal:  J Neurol Sci       Date:  2012-09-19       Impact factor: 3.181

Review 5.  Isolated posterior spinal artery aneurysm.

Authors:  A Koçak; O Ateş; S Rüştü Cayli; K Saraç
Journal:  Br J Neurosurg       Date:  2006-08       Impact factor: 1.596

6.  Solitary spinal artery aneurysms as a rare source of spinal subarachnoid hemorrhage: potential etiology and treatment strategy.

Authors:  Ansgar Berlis; Kai-Michael Scheufler; Christian Schmahl; Sebastian Rauer; Friedrich Götz; Martin Schumacher
Journal:  AJNR Am J Neuroradiol       Date:  2005-02       Impact factor: 3.825

7.  Subarachnoid haemorrhage with "Ecstasy" abuse in a young adult.

Authors:  J Auer; R Berent; T Weber; E Lassnig; B Eber
Journal:  Neurol Sci       Date:  2002-10       Impact factor: 3.307

8.  Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")

Authors:  J A Henry; K J Jeffreys; S Dawling
Journal:  Lancet       Date:  1992-08-15       Impact factor: 79.321

9.  Endovascular obliteration of a ruptured posterior spinal artery pseudoaneurysm.

Authors:  Omar Tanweer; Rona Woldenberg; Sarah Zwany; Avi Setton
Journal:  J Neurosurg Spine       Date:  2012-08-10

Review 10.  Multiple aneurysms of thoracic spinal cord arteries presenting with spinal infarction and subarachnoid hemorrhage: case report and literature review.

Authors:  Kenichi Sato; Luca Roccatagliata; Sebastien Depuydt; Georges Rodesch
Journal:  Neurosurgery       Date:  2012-11       Impact factor: 4.654

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  1 in total

Review 1.  Cerebrovascular and cardiovascular diseases caused by drugs of abuse.

Authors:  Yuichi Akasaki; Mitsuru Ohishi
Journal:  Hypertens Res       Date:  2019-12-05       Impact factor: 3.872

  1 in total

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