Xiaoke Li1, Jinfang Wang2, Andrew Joiner3, Jiang Chang4. 1. Unilever Oral Care, 66 Linxin Road, Shanghai, 200335, China. Electronic address: leo-sh.li@Unilever.com. 2. Unilever Oral Care, 66 Linxin Road, Shanghai, 200335, China. 3. Unilever Oral Care, Quarry Road East, Bebington, Wirral CH63 3JW, UK. 4. State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai, 200050, China.
Abstract
OBJECTIVE: The purpose of this paper is to review current knowledge and technologies for tooth remineralisation. DATA SOURCES: The literature was searched using the "Scopus" and "Web of Knowledge" database from the year 1971, with principal key words of *miner*, teeth and enamel. Language was restricted to English. Original studies and reviews were included. Conference papers and posters were excluded. CONCLUSION: The importance of oral health for patients and consumers has seen a steady increase in the number of tooth remineralisation agents, products and procedures over recent years. Concomitantly, there has been continued publication of both in vivo and in vitro tooth remineralisation and demineralisation studies. It is clear that fluoride treatments are generally effective in helping to protect the dental enamel from demineralisation and enhancing remineralisation. Continued efforts to increase the efficacy of fluoride have been made, in particular, by the addition of calcium salts or calcium containing materials to oral care products which may enhance the delivery and retention of fluoride into the oral cavity. In addition, the calcium salts or materials may act as additional sources of calcium to promote enamel remineralisation or reduce demineralisation processes. Inspired by the concept of bioactive materials for bone repair and regeneration, bioglass and in particular calcium silicate type materials show potential for enamel health benefits and is a growing area of research.
OBJECTIVE: The purpose of this paper is to review current knowledge and technologies for tooth remineralisation. DATA SOURCES: The literature was searched using the "Scopus" and "Web of Knowledge" database from the year 1971, with principal key words of *miner*, teeth and enamel. Language was restricted to English. Original studies and reviews were included. Conference papers and posters were excluded. CONCLUSION: The importance of oral health for patients and consumers has seen a steady increase in the number of tooth remineralisation agents, products and procedures over recent years. Concomitantly, there has been continued publication of both in vivo and in vitro tooth remineralisation and demineralisation studies. It is clear that fluoride treatments are generally effective in helping to protect the dental enamel from demineralisation and enhancing remineralisation. Continued efforts to increase the efficacy of fluoride have been made, in particular, by the addition of calcium salts or calcium containing materials to oral care products which may enhance the delivery and retention of fluoride into the oral cavity. In addition, the calcium salts or materials may act as additional sources of calcium to promote enamel remineralisation or reduce demineralisation processes. Inspired by the concept of bioactive materials for bone repair and regeneration, bioglass and in particular calcium silicate type materials show potential for enamel health benefits and is a growing area of research.
Authors: Raquel Marianna Lopes; T Scaramucci; Clandler L Walker; S A Feitosa; Ana Cecilia Correa Aranha Journal: Clin Oral Investig Date: 2021-05-11 Impact factor: 3.573