Literature DB >> 24993033

Driving glioblastoma growth by alternative polyadenylation.

Ting Han1, John K Kim2.   

Abstract

Global shortening of 3' untranslated regions (3' UTRs) through alternative polyadenylation is an emerging hallmark of cancer. A recent study identifies the cleavage factor Im 25 (CFIm25) as an important mediator of 3' UTR shortening in glioblastomas and demonstrates a causal relationship between alternative polyadenylation and cancer cell proliferation.

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Year:  2014        PMID： 24993033      PMCID： PMC4152745          DOI： 10.1038/cr.2014.88

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  10 in total

1.  Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites.

Authors:  Rickard Sandberg; Joel R Neilson; Arup Sarma; Phillip A Sharp; Christopher B Burge
Journal:  Science       Date:  2008-06-20       Impact factor: 47.728

2.  The landscape of C. elegans 3'UTRs.

Authors:  Marco Mangone; Arun Prasad Manoharan; Danielle Thierry-Mieg; Jean Thierry-Mieg; Ting Han; Sebastian D Mackowiak; Emily Mis; Charles Zegar; Michelle R Gutwein; Vishal Khivansara; Oliver Attie; Kevin Chen; Kourosh Salehi-Ashtiani; Marc Vidal; Timothy T Harkins; Pascal Bouffard; Yutaka Suzuki; Sumio Sugano; Yuji Kohara; Nikolaus Rajewsky; Fabio Piano; Kristin C Gunsalus; John K Kim
Journal:  Science       Date:  2010-06-03       Impact factor: 47.728

3.  Genome-wide analysis of pre-mRNA 3' end processing reveals a decisive role of human cleavage factor I in the regulation of 3' UTR length.

Authors:  Georges Martin; Andreas R Gruber; Walter Keller; Mihaela Zavolan
Journal:  Cell Rep       Date:  2012-06-07       Impact factor: 9.423

Review 4.  Mechanisms and consequences of alternative polyadenylation.

Authors:  Dafne Campigli Di Giammartino; Kensei Nishida; James L Manley
Journal:  Mol Cell       Date:  2011-09-16       Impact factor: 17.970

5.  ELAV mediates 3' UTR extension in the Drosophila nervous system.

Authors:  Valérie Hilgers; Sandra B Lemke; Michael Levine
Journal:  Genes Dev       Date:  2012-09-27       Impact factor: 11.361

6.  Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation.

Authors:  Fatih Ozsolak; Philipp Kapranov; Sylvain Foissac; Sang Woo Kim; Elane Fishilevich; A Paula Monaghan; Bino John; Patrice M Milos
Journal:  Cell       Date:  2010-12-10       Impact factor: 41.582

7.  Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells.

Authors:  Christine Mayr; David P Bartel
Journal:  Cell       Date:  2009-08-21       Impact factor: 41.582

8.  U1 snRNP determines mRNA length and regulates isoform expression.

Authors:  Michael G Berg; Larry N Singh; Ihab Younis; Qiang Liu; Anna Maria Pinto; Daisuke Kaida; Zhenxi Zhang; Sungchan Cho; Scott Sherrill-Mix; Lili Wan; Gideon Dreyfuss
Journal:  Cell       Date:  2012-07-06       Impact factor: 41.582

9.  Widespread and extensive lengthening of 3' UTRs in the mammalian brain.

Authors:  Pedro Miura; Sol Shenker; Celia Andreu-Agullo; Jakub O Westholm; Eric C Lai
Journal:  Genome Res       Date:  2013-03-21       Impact factor: 9.043

10.  CFIm25 links alternative polyadenylation to glioblastoma tumour suppression.

Authors:  Chioniso P Masamha; Zheng Xia; Jingxuan Yang; Todd R Albrecht; Min Li; Ann-Bin Shyu; Wei Li; Eric J Wagner
Journal:  Nature       Date:  2014-05-11       Impact factor: 49.962
  10 in total
  10 in total

Review 1.  Principles of miRNA-mRNA interactions: beyond sequence complementarity.

Authors:  Fabian Afonso-Grunz; Sören Müller
Journal:  Cell Mol Life Sci       Date:  2015-06-03       Impact factor: 9.261

Review 2.  CFIm25 and alternative polyadenylation: Conflicting roles in cancer.

Authors:  Mohammad Hassan Jafari Najaf Abadi; Rana Shafabakhsh; Zatollah Asemi; Hamid Reza Mirzaei; Roxana Sahebnasagh; Hamed Mirzaei; Michael R Hamblin
Journal:  Cancer Lett       Date:  2019-06-07       Impact factor: 8.679

3.  CFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis.

Authors:  Souvik Ghosh; Meric Ataman; Maciej Bak; Anastasiya Börsch; Alexander Schmidt; Katarzyna Buczak; Georges Martin; Beatrice Dimitriades; Christina J Herrmann; Alexander Kanitz; Mihaela Zavolan
Journal:  Nucleic Acids Res       Date:  2022-04-08       Impact factor: 16.971

4.  Ribonucleic acid (RNA) biosynthesis in human cancer.

Authors:  Omar S Hajjawi
Journal:  Cancer Cell Int       Date:  2015-02-21       Impact factor: 5.722

5.  ETV2 mediates endothelial transdifferentiation of glioblastoma.

Authors:  Chengjian Zhao; Gustavo A Gomez; Yuwei Zhao; Yu Yang; Dan Cao; Jing Lu; Hanshuo Yang; Shuo Lin
Journal:  Signal Transduct Target Ther       Date:  2018-02-09

Review 6.  Emerging Roles of RNA 3'-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders.

Authors:  Jamie Nourse; Stefano Spada; Sven Danckwardt
Journal:  Biomolecules       Date:  2020-06-17

7.  CFIm25 in Solid Tumors: Current Research Progress.

Authors:  Xiaojie Sun; Ji Li; Xun Sun; Wanqi Liu; Xiangwei Meng
Journal:  Technol Cancer Res Treat       Date:  2020 Jan-Dec

Review 8.  MicroRNAs as Emerging Regulators of Signaling in the Tumor Microenvironment.

Authors:  Shahzad Nawaz Syed; Bernhard Brüne
Journal:  Cancers (Basel)       Date:  2020-04-08       Impact factor: 6.639

Review 9.  The Butterfly Effect of RNA Alterations on Transcriptomic Equilibrium.

Authors:  Ng Desi; Yvonne Tay
Journal:  Cells       Date:  2019-12-13       Impact factor: 6.600

10.  CFIm25 inhibits hepatocellular carcinoma metastasis by suppressing the p38 and JNK/c-Jun signaling pathways.

Authors:  Yunwu Wang; Yu Xu; Wei Yan; Ping Han; Jingmei Liu; Jin Gong; Dongxiao Li; Xiangming Ding; Han Wang; Zhuoying Lin; Dean Tian; Jiazhi Liao
Journal:  Oncotarget       Date:  2018-01-31
  10 in total

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