Literature DB >> 24991368

Burden of Disease: The Psychosocial Impact of Rosacea on a Patient's Quality of Life.

Tu T Huynh1.   

Abstract

BACKGROUND: Rosacea is a chronic skin disorder that adversely affects patients' quality of life. Current studies focus on the therapies that treat the clinical signs and symptoms of rosacea, but the impact of this disease on patients' emotional health and quality of life is often overlooked.
OBJECTIVES: To describe the disease burden of rosacea and the psychosocial implications on patients' quality of life and to review the current understanding of the disease and the available therapies. DISCUSSION: The facial skin manifestations of rosacea have significant implications on patients' well-being and social and emotional health. The 4 clinical subtypes of this disease include erythematotelangiectatic, papulopustular, phymatous, and ocular, and patients may present with more than 1 subtype. Patients with rosacea have reported a negative burden of their disease, such as low self-esteem, low self-confidence, and decreased social interactions. Improvement of the clinical symptoms of rosacea improves the patient's emotional well-being and quality of life. Several topical medications and 1 oral medication have been approved for the treatment of rosacea. Although current therapies do not cure the disease and do not treat the facial erythema associated with it, they do treat the papules and pustules associated with this condition. Proper management of the signs and symptoms of rosacea has been shown to improve patients' quality of life.
CONCLUSION: The self-perception of disease severity varies among patients with rosacea, so physicians should carefully consider each patient's concerns when prescribing a treatment regimen. Although no cure exists, effective treatment options aid in the management of signs and symptoms of rosacea. New therapies that treat the broad range of rosacea symptoms are needed.

Entities:  

Year:  2013        PMID: 24991368      PMCID: PMC4031723     

Source DB:  PubMed          Journal:  Am Health Drug Benefits        ISSN: 1942-2962


  62 in total

1.  Stress and the skin.

Authors:  A Reich; A Wójcik-Maciejewicz; A T Slominski
Journal:  G Ital Dermatol Venereol       Date:  2010-04       Impact factor: 2.011

2.  Rosacea in patients with skin of color: uncommon but not rare.

Authors:  Andrew F Alexis
Journal:  Cutis       Date:  2010-08

3.  A pilot quality-of-life instrument for acne rosacea.

Authors:  Kimberly Nicholson; Liana Abramova; Mary-Margaret Chren; Jensen Yeung; Susan Y Chon; Suephy C Chen
Journal:  J Am Acad Dermatol       Date:  2007-04-18       Impact factor: 11.527

Review 4.  Azelaic acid 15% gel in the treatment of rosacea.

Authors:  Harald Gollnick; Alison Layton
Journal:  Expert Opin Pharmacother       Date:  2008-10       Impact factor: 3.889

5.  The efficacy of metronidazole 1% cream once daily compared with metronidazole 1% cream twice daily and their vehicles in rosacea: a double-blind clinical trial.

Authors:  J L Jorizzo; M Lebwohl; R E Tobey
Journal:  J Am Acad Dermatol       Date:  1998-09       Impact factor: 11.527

Review 6.  Rosacea.

Authors:  A Rebora
Journal:  J Invest Dermatol       Date:  1987-03       Impact factor: 8.551

7.  Positive correlation between serum immunoreactivity to Demodex-associated Bacillus proteins and erythematotelangiectatic rosacea.

Authors:  N O'Reilly; N Menezes; K Kavanagh
Journal:  Br J Dermatol       Date:  2012-09-25       Impact factor: 9.302

8.  Skin disease and stigma in emerging adulthood: impact on healthy development.

Authors:  Neda Roosta; David S Black; David Peng; Lee W Riley
Journal:  J Cutan Med Surg       Date:  2010 Nov-Dec       Impact factor: 2.092

9.  Willingness to pay and time trade-off: sensitive to changes of quality of life in psoriasis patients?

Authors:  R Schiffner; J Schiffner-Rohe; M Gerstenhauer; F Hofstädter; M Landthaler; W Stolz
Journal:  Br J Dermatol       Date:  2003-06       Impact factor: 9.302

10.  Willingness to pay and quality of life in patients with rosacea.

Authors:  F C Beikert; A K Langenbruch; M A Radtke; M Augustin
Journal:  J Eur Acad Dermatol Venereol       Date:  2012-05-14       Impact factor: 6.166

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  17 in total

1.  Soolantra (Ivermectin) 1% Cream: A Novel, Antibiotic-Free Agent Approved for the Treatment of Patients with Rosacea.

Authors:  Lisa A Raedler
Journal:  Am Health Drug Benefits       Date:  2015-03

2.  Botulinum toxin blocks mast cells and prevents rosacea like inflammation.

Authors:  Jae Eun Choi; Tyler Werbel; Zhenping Wang; Chia Chi Wu; Tony L Yaksh; Anna Di Nardo
Journal:  J Dermatol Sci       Date:  2018-12-28       Impact factor: 4.563

3.  Safety and Pharmacokinetics of FMX103 (1.5% Minocycline Topical Foam) in Subjects with Moderate-to-Severe Papulopustular Rosacea under Maximum-use Treatment Conditions.

Authors:  Terry M Jones; Iain Stuart
Journal:  J Clin Aesthet Dermatol       Date:  2021-03-01

4.  Biophotonic Therapy with Fluorescent Light Energy Decreases Facial Erythema, Improves Signs and Symptoms of Rosacea, and Increases Patient Satisfaction: A Postmarket Study.

Authors:  Martin Wade; Vanessa Charest; Bruno Ballardin; Deirdre Edge; Michael Canova Engelbrecht Nielsen
Journal:  J Clin Aesthet Dermatol       Date:  2021-07-01

5.  Quality of Life in Individuals with Erythematotelangiectatic and Papulopustular Rosacea: Findings From a Web-based Survey.

Authors:  Joshua A Zeichner; Lawrence F Eichenfield; Steven R Feldman; J Scott Kasteler; Ilia L Ferrusi
Journal:  J Clin Aesthet Dermatol       Date:  2018-02-01

6.  The Burden of Illness of Erythematotelangiectatic Rosacea and Papulopustular Rosacea: Findings From a Web-based Survey.

Authors:  James Q Del Rosso; Emil A Tanghetti; Hilary E Baldwin; David A Rodriguez; Ilia L Ferrusi
Journal:  J Clin Aesthet Dermatol       Date:  2017-06-01

7.  Metronidazole gel (0.75%) in Japanese patients with rosacea: A randomized, vehicle-controlled, phase 3 study.

Authors:  Yoshiki Miyachi; Kenshi Yamasaki; Tomomitsu Fujita; Chie Fujii
Journal:  J Dermatol       Date:  2021-12-01       Impact factor: 3.468

8.  Perceptions on the Psychological Impact of Facial Erythema Associated with Rosacea: Results of International Survey.

Authors:  Thomas Dirschka; Giuseppe Micali; Linda Papadopoulos; Jerry Tan; Alison Layton; Simon Moore
Journal:  Dermatol Ther (Heidelb)       Date:  2015-05-29

9.  Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in China.

Authors:  Mengting Chen; Zhili Deng; Yingxue Huang; Ji Li
Journal:  Front Psychiatry       Date:  2021-06-16       Impact factor: 4.157

10.  The efficacy, safety, and tolerability of ivermectin compared with current topical treatments for the inflammatory lesions of rosacea: a network meta-analysis.

Authors:  Kashif Siddiqui; Linda Stein Gold; Japinder Gill
Journal:  Springerplus       Date:  2016-07-22
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