Literature DB >> 24991313

Trends in biologic therapies for rheumatoid arthritis: results from a survey of payers and providers.

Rhonda Greenapple1.   

Abstract

BACKGROUND: Advances in therapies for rheumatoid arthritis (RA), particularly biologics, have transformed the treatment paradigm for RA. However, the associated costs of these therapies result in a significant economic burden on the healthcare system. As a chronic disease requiring lifelong treatment, most health plans now position RA drugs as a high-priority therapeutic category.
OBJECTIVE: To identify provider and payer practices and perceptions regarding coverage of RA biologics in the current marketplace, as well as emerging trends in reimbursement practices.
METHOD: In November 2011, Reimbursement Intelligence, a healthcare research company, collected and analyzed quantitative and qualitative data via parallel-structure online surveys of 100 rheumatologists and 50 health plan payers (medical and pharmacy directors) who represent more than 80 million covered lives. The surveys included approximately 150 questions, and the surveys were designed to force a response for each question.
RESULTS: Payers reported using tier placement, prior authorization, and contracting in determining coverage strategies for RA biologics. Among providers, experience with older RA agents remains the key driver for the choice of a biologic agent. A majority of payers and providers (68% and 54%, respectively) reported that they did not anticipate a change in the way their plans would manage biologics over the next 2 to 4 years. Payers' responses indicated uncertainty about how therapeutic positioning of newer, small-molecule drugs at price parity to biologics would affect the current reimbursement landscape. Survey responses show that approval of an indication for early treatment of RA is not likely to change the prescribing and reimbursement landscape for RA biologics. This survey further shows that payers and providers are generally aligned in terms of perceptions of current and future treatments for RA.
CONCLUSION: Advances in RA therapies allow patients increasing options for effective disease management. However, the high cost of biologic therapies and the need for lifelong treatment raise economic concerns. Payer satisfaction with current therapies and uncertainty about added value of new therapies will create challenges for new medications coming to market.

Entities:  

Year:  2012        PMID: 24991313      PMCID: PMC4046448     

Source DB:  PubMed          Journal:  Am Health Drug Benefits        ISSN: 1942-2962


  9 in total

Review 1.  Overview of work disability in rheumatoid arthritis patients as observed in cross-sectional and longitudinal surveys.

Authors:  S M M Verstappen; J W J Bijlsma; H Verkleij; E Buskens; A A M Blaauw; E J ter Borg; J W G Jacobs
Journal:  Arthritis Rheum       Date:  2004-06-15

2.  2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative.

Authors:  Daniel Aletaha; Tuhina Neogi; Alan J Silman; Julia Funovits; David T Felson; Clifton O Bingham; Neal S Birnbaum; Gerd R Burmester; Vivian P Bykerk; Marc D Cohen; Bernard Combe; Karen H Costenbader; Maxime Dougados; Paul Emery; Gianfranco Ferraccioli; Johanna M W Hazes; Kathryn Hobbs; Tom W J Huizinga; Arthur Kavanaugh; Jonathan Kay; Tore K Kvien; Timothy Laing; Philip Mease; Henri A Ménard; Larry W Moreland; Raymond L Naden; Theodore Pincus; Josef S Smolen; Ewa Stanislawska-Biernat; Deborah Symmons; Paul P Tak; Katherine S Upchurch; Jirí Vencovsky; Frederick Wolfe; Gillian Hawker
Journal:  Ann Rheum Dis       Date:  2010-09       Impact factor: 19.103

3.  American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis.

Authors:  Kenneth G Saag; Gim Gee Teng; Nivedita M Patkar; Jeremy Anuntiyo; Catherine Finney; Jeffrey R Curtis; Harold E Paulus; Amy Mudano; Maria Pisu; Mary Elkins-Melton; Ryan Outman; Jeroan J Allison; Maria Suarez Almazor; S Louis Bridges; W Winn Chatham; Marc Hochberg; Catherine MacLean; Ted Mikuls; Larry W Moreland; James O'Dell; Anthony M Turkiewicz; Daniel E Furst
Journal:  Arthritis Rheum       Date:  2008-06-15

Review 4.  Rheumatoid arthritis.

Authors:  D M Lee; M E Weinblatt
Journal:  Lancet       Date:  2001-09-15       Impact factor: 79.321

Review 5.  Diagnosis and management of rheumatoid arthritis.

Authors:  J Adam Rindfleisch; Daniel Muller
Journal:  Am Fam Physician       Date:  2005-09-15       Impact factor: 3.292

6.  Is the incidence of rheumatoid arthritis rising?: results from Olmsted County, Minnesota, 1955-2007.

Authors:  Elena Myasoedova; Cynthia S Crowson; Hilal Maradit Kremers; Terry M Therneau; Sherine E Gabriel
Journal:  Arthritis Rheum       Date:  2010-06

Review 7.  Aggressive treatment of early rheumatoid arthritis: recognizing the window of opportunity and treating to target goals.

Authors:  Beth H Resman-Targoff; Marco P Cicero
Journal:  Am J Manag Care       Date:  2010-11       Impact factor: 2.229

8.  Contemporary prevalence and incidence of work disability associated with rheumatoid arthritis in the US.

Authors:  Saralynn Allaire; Frederick Wolfe; Jingbo Niu; Michael P Lavalley
Journal:  Arthritis Rheum       Date:  2008-04-15

Review 9.  Work disability in early rheumatoid arthritis.

Authors:  T Sokka
Journal:  Clin Exp Rheumatol       Date:  2003 Sep-Oct       Impact factor: 4.473

  9 in total
  6 in total

1.  Considering patient preferences when selecting anti-tumor necrosis factor therapeutic options.

Authors:  Gosia Sylwestrzak; Jinan Liu; Judith J Stephenson; Alexander P Ruggieri; Andrea DeVries
Journal:  Am Health Drug Benefits       Date:  2014-04

2.  Cost-Effectiveness of Repository Corticotropin Injection versus Standard of Care for the Treatment of Active Rheumatoid Arthritis.

Authors:  Jas Bindra; Ishveen Chopra; John Niewoehner; Mary Panaccio; George J Wan
Journal:  Clinicoecon Outcomes Res       Date:  2021-05-06

3.  Treatment Patterns of Newly Diagnosed Rheumatoid Arthritis Patients from a Commercially Insured Population.

Authors:  David M Kern; Lawrence Chang; Kalyani Sonawane; Cynthia J Larmore; Natalie N Boytsov; Ralph A Quimbo; Joseph Singer; John T Hinton; Sze-Jung Wu; Andre B Araujo
Journal:  Rheumatol Ther       Date:  2018-05-30

4.  Factors influencing the use of biologic therapy and adoption of treat-to-target recommendations in current European rheumatology practice.

Authors:  Peter C Taylor; Rieke Alten; Juan J Gomez Reino; Roberto Caporali; Philippe Bertin; Emma Sullivan; Robert Wood; James Piercy; Radu Vasilescu; Dean Spurden; Jose Alvir; Miriam Tarallo
Journal:  Patient Prefer Adherence       Date:  2018-10-04       Impact factor: 2.711

5.  The Effectiveness of Intravenous Golimumab Administered Directly After Infliximab in Rheumatoid Arthritis Patients.

Authors:  Vance J Bray; Aaron Broadwell; Herbert S B Baraf; Shawn Black; Brenna L Brady; Joseph Tkacz; Lorraine Yarngo; Raphael J DeHoratius
Journal:  Drugs R D       Date:  2018-09

6.  Factors associated with physicians' prescriptions for rheumatoid arthritis drugs not filled by patients.

Authors:  Hong J Kan; Kirill Dyagilev; Peter Schulam; Suchi Saria; Hadi Kharrazi; David Bodycombe; Charles T Molta; Jeffrey R Curtis
Journal:  Arthritis Res Ther       Date:  2018-05-02       Impact factor: 5.156

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.