Literature DB >> 24990848

Aleukaemic leukaemia presenting with pathological fracture.

Gilbert T Chua1, Kam Ching Chow2, Jason Chi Chiu So3, Daniel Ka Leung Cheuk4.   

Abstract

A 19-month-old Chinese girl presented with pathological fracture of her right distal tibia. Peripheral blood revealed no abnormal cells, electrolytes were normal and bone biopsy at the fracture site only showed small aggregates of unremarkable lymphocytes. A bone marrow study could not provide a definitive diagnosis of acute leukaemia on morphology and immunohistochemistry. A diagnosis of precursor B-cell acute lymphoblastic leukaemia was unequivocally confirmed by a cytogenetic study which showed a hyperdiploid clone with gain of chromosome 4 among other trisomies. 2014 BMJ Publishing Group Ltd.

Entities:  

Mesh:

Year:  2014        PMID: 24990848      PMCID: PMC4091132          DOI: 10.1136/bcr-2014-204690

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  16 in total

1.  Multiple vertebral collapse as a presentation of childhood acute lymphoblastic leukaemia.

Authors:  R Desmond; J McDerra; K Kelly; O Smith
Journal:  Br J Haematol       Date:  2008-10-18       Impact factor: 6.998

2.  Musculoskeletal conditions of acute leukemia and malignant lymphoma in children.

Authors:  Daisuke Kobayashi; Shinichi Satsuma; Makoto Kamegaya; Nobuhiko Haga; Satoshi Shimomura; Toshio Fujii; Shinichi Yoshiya
Journal:  J Pediatr Orthop B       Date:  2005-05       Impact factor: 1.041

Review 3.  Biology, risk stratification, and therapy of pediatric acute leukemias: an update.

Authors:  Ching-Hon Pui; William L Carroll; Soheil Meshinchi; Robert J Arceci
Journal:  J Clin Oncol       Date:  2011-01-10       Impact factor: 44.544

4.  Aleukemic leukemia cutis in a child preceding T-cell acute lymphoblastic leukemia.

Authors:  Nabeel Najem; Valid B Zadeh; Mona Badawi; Ramesh Kumar; Sultan Al-Otaibi; Adel Al-Abdulrazzaq
Journal:  Pediatr Dermatol       Date:  2011-09-05       Impact factor: 1.588

5.  Granulocytic sarcoma of gingiva: an unusual case with aleukemic presentation.

Authors:  B Antmen; M C Haytac; I Sasmaz; M C Dogan; M Ergin; A Tanyeli
Journal:  J Periodontol       Date:  2003-10       Impact factor: 6.993

6.  Mineral homeostasis and bone mass at diagnosis in children with acute lymphoblastic leukemia.

Authors:  J M Halton; S A Atkinson; L Fraher; C E Webber; W P Cockshott; C Tam; R D Barr
Journal:  J Pediatr       Date:  1995-04       Impact factor: 4.406

7.  An unusual presentation of pediatric acute lymphoblastic leukemia.

Authors:  Sonali Sadawaite; Farah Jijina; Chandran K Nair; Sishir Seth; Kanjaksha Ghosh
Journal:  Indian J Hematol Blood Transfus       Date:  2008-05-16       Impact factor: 0.900

8.  Back pain and vertebral compression: an uncommon presentation of childhood acute lymphoblastic leukemia.

Authors:  G M Samuda; M Y Cheng; C Y Yeung
Journal:  J Pediatr Orthop       Date:  1987 Mar-Apr       Impact factor: 2.324

9.  Granulocytic sarcoma of breast: an aleukemic presentation.

Authors:  Grace F D'Costa; Meenal S Hastak; Yoganand V Patil
Journal:  Indian J Med Sci       Date:  2007-03

10.  Initial presentation of acute lymphoblastic leukemia with osteoporosis and multiple spontaneous bone fractures.

Authors:  N Cohan; S Sarikhani; S Moslemi; M Karimi
Journal:  Iran Red Crescent Med J       Date:  2011-01-01       Impact factor: 0.611

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  2 in total

1.  Acute Lymphoblastic Leukemia presenting as a Pathologic Fibular Fracture.

Authors:  Aditi Iyer; Rohan Mangal; Thor Stead; Andrew Barbera
Journal:  Orthop Rev (Pavia)       Date:  2022-08-25

2.  Vertebral Compression Fractures-The First Manifestations in the Elderly Acute Lymphoblastic Leukemia.

Authors:  Cheng Liu; Cuili Shu
Journal:  Geriatr Orthop Surg Rehabil       Date:  2021-06-22
  2 in total

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