Literature DB >> 24989776

Mortality after hip fracture in Austria 2008-2011.

Wolfgang Brozek1, Berthold Reichardt, Oliver Kimberger, Jochen Zwerina, Hans Peter Dimai, Daniela Kritsch, Klaus Klaushofer, Elisabeth Zwettler.   

Abstract

Osteoporosis-related hip fractures represent a substantial cause of mortality and morbidity in industrialized countries like Austria. Identification of groups at high risk for mortality after hip fracture is crucial for health policy decisions. To determine in-hospital, long-term, and excess mortality after osteoporosis-related hip fracture in Austrian patients, we conducted a retrospective cohort analysis of pseudonymized invoice data from Austrian social insurance authorities covering roughly 98 % of the entire population. The data set included 31,668 subjects aged 50 years and above sustaining a hip fracture between July 2008 and December 2010 with follow-up until June 2011, and an age-, gender-, and regionally matched control population without hip fractures (56,320 subjects). Kaplan-Meier and Cox hazard regression analyses served to determine unadjusted and adjusted mortality rates: Unadjusted all-cause 1-year mortality amounted to 20.2 % (95 % CI: 19.7-20.7 %). Males had significantly higher long-term, in-hospital, and excess mortality rates than females, but younger males exhibited lower excess mortality than their female counterparts. Advanced age correlated with increased long-term and in-hospital mortality, but lower excess mortality. Excess mortality, particularly in males, was highest in the first 6 months after hip fracture, but remained statistically significantly elevated throughout the observation period of 3 years. Longer hospital stay per fracture was correlated with mortality reduction in older patients and in patients with more subsequent fractures. In conclusion, more efforts are needed to identify causes and effectively prevent excess mortality especially in male osteoporosis patients.

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Year:  2014        PMID: 24989776     DOI: 10.1007/s00223-014-9889-9

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN: 0171-967X            Impact factor:   4.333


  19 in total

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Authors:  W Brozek; B Reichardt; J Zwerina; H P Dimai; K Klaushofer; E Zwettler
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4.  Risk Factors Associated with Dislocation after Bipolar Hemiarthroplasty in Elderly Patients with Femoral Neck Fracture.

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5.  Excess of all-cause mortality after a fracture in type 2 diabetic patients: a population-based cohort study.

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6.  Antiresorptive therapy and risk of mortality and refracture in osteoporosis-related hip fracture: a nationwide study.

Authors:  W Brozek; B Reichardt; J Zwerina; H P Dimai; K Klaushofer; E Zwettler
Journal:  Osteoporos Int       Date:  2015-11-17       Impact factor: 4.507

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Journal:  Ann Geriatr Med Res       Date:  2021-06-25

8.  Association between gastrointestinal events and osteoporosis treatment initiation in women diagnosed with osteoporosis in France: a retrospective analysis.

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9.  Gastrointestinal symptoms and association with medication use patterns, adherence, treatment satisfaction, quality of life, and resource use in osteoporosis: baseline results of the MUSIC-OS study.

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10.  Nonoperative hip fracture management practices and patient survival compared to surgical care: an analysis of Estonian population-wide data.

Authors:  Pärt Prommik; Kaspar Tootsi; Toomas Saluse; Aare Märtson; Helgi Kolk
Journal:  Arch Osteoporos       Date:  2021-06-25       Impact factor: 2.617

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