Literature DB >> 24986668

Update on biological therapies for knee injuries: osteoarthritis.

Guilherme Figueiredo Pintan1, Adilson Sanches de Oliveira, Mario Lenza, Eliane Antonioli, Mario Ferretti.   

Abstract

Osteoarthritis (OA) is a progressive disease that causes functional impairment of the joints. Chronic forms of knee OA have been increasing worldwide, limiting patients' quality of life. Recent studies have sought to increase effectiveness and quality in the development of new therapies, such as platelet-rich plasma, hyaluronic acid, stem cells, and nuclear factor κB, aimed principally at reducing proinflammatory activity, pain, and degeneration of the knee joints. The goal of this review is to present an update on biological therapies for knee OA and to provide guidance for future OA studies.

Entities:  

Year:  2014        PMID: 24986668      PMCID: PMC4596155          DOI: 10.1007/s12178-014-9229-8

Source DB:  PubMed          Journal:  Curr Rev Musculoskelet Med        ISSN: 1935-9748


  39 in total

1.  Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized, double-blind, dose-escalation, placebo-controlled study.

Authors:  H Nagashima; M Suzuki; S Araki; T Yamabe; C Muto
Journal:  Osteoarthritis Cartilage       Date:  2011-10-05       Impact factor: 6.576

2.  The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study.

Authors:  Marita Cross; Emma Smith; Damian Hoy; Sandra Nolte; Ilana Ackerman; Marlene Fransen; Lisa Bridgett; Sean Williams; Francis Guillemin; Catherine L Hill; Laura L Laslett; Graeme Jones; Flavia Cicuttini; Richard Osborne; Theo Vos; Rachelle Buchbinder; Anthony Woolf; Lyn March
Journal:  Ann Rheum Dis       Date:  2014-02-19       Impact factor: 19.103

3.  Osteoarthrosis of the knee. A radiographic investigation.

Authors:  S Ahlbäck
Journal:  Acta Radiol Diagn (Stockh)       Date:  1968

Review 4.  Role of proinflammatory cytokines in the pathophysiology of osteoarthritis.

Authors:  Mohit Kapoor; Johanne Martel-Pelletier; Daniel Lajeunesse; Jean-Pierre Pelletier; Hassan Fahmi
Journal:  Nat Rev Rheumatol       Date:  2010-11-30       Impact factor: 20.543

5.  Growth factors in the treatment of early osteoarthritis.

Authors:  Roberto Civinini; Lorenzo Nistri; Caterina Martini; Birgit Redl; Gabriele Ristori; Massimo Innocenti
Journal:  Clin Cases Miner Bone Metab       Date:  2013-01

6.  Age- and gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors.

Authors:  G F Muschler; H Nitto; C A Boehm; K A Easley
Journal:  J Orthop Res       Date:  2001-01       Impact factor: 3.494

Review 7.  Stem cells in clinical practice: applications and warnings.

Authors:  Daniele Lodi; Tommaso Iannitti; Beniamino Palmieri
Journal:  J Exp Clin Cancer Res       Date:  2011-01-17

Review 8.  The future of osteoarthritis therapeutics: emerging biological therapy.

Authors:  A Mobasheri
Journal:  Curr Rheumatol Rep       Date:  2013-12       Impact factor: 4.592

9.  Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial.

Authors:  Jean-Yves Reginster; Janusz Badurski; Nicholas Bellamy; William Bensen; Roland Chapurlat; Xavier Chevalier; Claus Christiansen; Harry Genant; Federico Navarro; Evgeny Nasonov; Philip N Sambrook; Timothy D Spector; Cyrus Cooper
Journal:  Ann Rheum Dis       Date:  2012-11-01       Impact factor: 19.103

10.  The role of stem cells in osteoarthritis: An experimental study in rabbits.

Authors:  A Singh; S C Goel; K K Gupta; M Kumar; G R Arun; H Patil; V Kumaraswamy; S Jha
Journal:  Bone Joint Res       Date:  2014-02-13       Impact factor: 5.853

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  3 in total

1.  Molecular Validation of Chondrogenic Differentiation and Hypoxia Responsiveness of Platelet-Lysate Expanded Adipose Tissue-Derived Human Mesenchymal Stromal Cells.

Authors:  Catalina Galeano-Garces; Emily T Camilleri; Scott M Riester; Amel Dudakovic; Dirk R Larson; Wenchun Qu; Jay Smith; Allan B Dietz; Hee-Jeong Im; Aaron J Krych; A Noelle Larson; Marcel Karperien; Andre J van Wijnen
Journal:  Cartilage       Date:  2016-07-21       Impact factor: 4.634

Review 2.  Stem cells in degenerative orthopaedic pathologies: effects of aging on therapeutic potential.

Authors:  Kivanc Atesok; Freddie H Fu; Ichiro Sekiya; Alexandra Stolzing; Mitsuo Ochi; Scott A Rodeo
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-08-23       Impact factor: 4.342

Review 3.  Intra-articular treatment of knee osteoarthritis: from anti-inflammatories to products of regenerative medicine.

Authors:  Masters M Richards; Joshua Shane Maxwell; Lihui Weng; Mathew G Angelos; Jafar Golzarian
Journal:  Phys Sportsmed       Date:  2016-04-04       Impact factor: 2.241

  3 in total

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