Literature DB >> 24983216

Leukotriene A4 hydrolase: the Janus enzyme shows its ugly side in smokers.

Robert Snelgrove1, Farrah Kheradmand.   

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Year:  2014        PMID： 24983216      PMCID： PMC4226033          DOI： 10.1164/rccm.201405-0975ED

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


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  15 in total

Review 1.  Autoimmunity in chronic obstructive pulmonary disease: clinical and experimental evidence.

Authors:  Farrah Kheradmand; Ming Shan; Chuang Xu; David B Corry
Journal:  Expert Rev Clin Immunol       Date:  2012-03       Impact factor: 4.473

2.  A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation.

Authors:  Robert J Snelgrove; Patricia L Jackson; Matthew T Hardison; Brett D Noerager; Andrew Kinloch; Amit Gaggar; Suresh Shastry; Steven M Rowe; Yun M Shim; Tracy Hussell; J Edwin Blalock
Journal:  Science       Date:  2010-09-02       Impact factor: 47.728

3.  Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.

Authors:  Saskia Braber; Pim J Koelink; Paul A J Henricks; Patricia L Jackson; Frans P Nijkamp; Johan Garssen; Aletta D Kraneveld; J Edwin Blalock; Gert Folkerts
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2010-11-26       Impact factor: 5.464

4.  An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease.

Authors:  J Michael Wells; Philip J O'Reilly; Tomasz Szul; Daniel I Sullivan; Guy Handley; Chris Garrett; Carmel M McNicholas; Mojtaba Abdul Roda; Bruce E Miller; Ruth Tal-Singer; Amit Gaggar; Stephen I Rennard; Patricia L Jackson; J Edwin Blalock
Journal:  Am J Respir Crit Care Med       Date:  2014-07-01       Impact factor: 21.405

5.  A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.

Authors:  Nathaniel M Weathington; Anneke H van Houwelingen; Brett D Noerager; Patricia L Jackson; Aletta D Kraneveld; F Shawn Galin; Gert Folkerts; Frans P Nijkamp; J Edwin Blalock
Journal:  Nat Med       Date:  2006-02-12       Impact factor: 53.440

6.  Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial.

Authors:  Jin-Ping Zheng; Fu-Qiang Wen; Chun-Xue Bai; Huan-Ying Wan; Jian Kang; Ping Chen; Wan-Zhen Yao; Li-Jun Ma; Xia Li; Luca Raiteri; Marco Sardina; Yi Gao; Bai-Song Wang; Nan-Shan Zhong
Journal:  Lancet Respir Med       Date:  2014-01-30       Impact factor: 30.700

7.  Cigarette smoke enhances chemotaxis via acetylation of proline-glycine-proline.

Authors:  Matthew Thomas Hardison; Michael David Brown; Robert James Snelgrove; James Edwin Blalock; Patricia Jackson
Journal:  Front Biosci (Elite Ed)       Date:  2012-06-01

8.  Autoreactive T Cells in Human Smokers is Predictive of Clinical Outcome.

Authors:  Chuang Xu; Sean Hesselbacher; Chu-Lin Tsai; Ming Shan; Margaret Spitz; Michael Scheurer; Luz Roberts; Sarah Perusich; Nazanin Zarinkamar; Harvey Coxson; Natasha Krowchuk; David B Corry; Farrah Kheradmand
Journal:  Front Immunol       Date:  2012-08-27       Impact factor: 7.561

9.  N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD.

Authors:  Philip O'Reilly; Patricia L Jackson; Brett Noerager; Suzanne Parker; Mark Dransfield; Amit Gaggar; J Edwin Blalock
Journal:  Respir Res       Date:  2009-05-18

10.  Sputum PGP is reduced by azithromycin treatment in patients with COPD and correlates with exacerbations.

Authors:  Philip J O'Reilly; Patricia L Jackson; J Michael Wells; Mark T Dransfield; Paul D Scanlon; J Edwin Blalock
Journal:  BMJ Open       Date:  2013-12-23       Impact factor: 2.692
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  3 in total

Review 1.  MMP generated matrikines.

Authors:  J Michael Wells; Amit Gaggar; J Edwin Blalock
Journal:  Matrix Biol       Date:  2015-01-28       Impact factor: 11.583

2.  Substrate-dependent modulation of the leukotriene A4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation.

Authors:  Kyung Hyeon Lee; Nadia Fazal Ali; Soo Hyeon Lee; Zhimin Zhang; Marie Burdick; Zachary J Beaulac; Greg Petruncio; Linxia Li; Jiangdong Xiang; Ezra M Chung; Kenneth W Foreman; Schroeder M Noble; Yun M Shim; Mikell Paige
Journal:  Sci Rep       Date:  2022-06-08       Impact factor: 4.996

3.  The development of novel LTA4H modulators to selectively target LTB4 generation.

Authors:  Caroline M Low; Samia Akthar; Dhiren F Patel; Stephan Löser; Chi-Tung Wong; Patricia L Jackson; J Edwin Blalock; Stephen A Hare; Clare M Lloyd; Robert J Snelgrove
Journal:  Sci Rep       Date:  2017-03-17       Impact factor: 4.379
  3 in total

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