Literature DB >> 24982596

Mercury free microscopy: an opportunity for core facility directors.

T Regan Baird1, Daniel Kaufman2, Claire M Brown2.   

Abstract

Mercury Free Microscopy (MFM) is a new movement that encourages microscope owners to choose modern mercury free light sources to replace more traditional mercury based arc lamps. Microscope performance is enhanced with new solid state technologies because they offer a more stable light intensity output and have a more uniform light output across the visible spectrum. Solid state sources not only eliminate mercury but also eliminate the cost of consumable bulbs (lifetime ∼200 hours), use less energy, reduce the instrument down time when bulbs fail and reduce the staff time required to replace and align bulbs. With lifetimes on the order of tens of thousands of hours, solid state replacements can pay for themselves over their lifetime with the omission of consumable, staff (no need to replace and align bulbs) and energy costs. Solid state sources are also sustainable and comply with institutional and government body mandates to reduce energy consumption, carbon footprints and hazardous waste. MFM can be used as a mechanism to access institutional financial resources for sustainable technology through a variety of stakeholders to defray the cost to microscope owners for the initial purchase of solid state sources or the replacement cost of mercury based sources. Core facility managers can take a lead in this area as "green" ambassadors for their institution by championing a local MFM program that will save their institution money and energy and eliminate mercury from the waste stream. Managers can leverage MFM to increase the visibility of their facility, their impact within the institution, and as a vital educational resource for scientific and administrative consultation.

Entities:  

Keywords:  fluorescence imaging; funding opportunities; light engines; light source

Mesh:

Substances:

Year:  2014        PMID: 24982596      PMCID: PMC3970759          DOI: 10.7171/jbt.14-2502-001

Source DB:  PubMed          Journal:  J Biomol Tech        ISSN: 1524-0215


  7 in total

Review 1.  Light-emitting diodes in modern microscopy--from David to Goliath?

Authors:  Johannes T Wessels; Uwe Pliquett; Fred S Wouters
Journal:  Cytometry A       Date:  2012-01-30       Impact factor: 4.355

2.  Light emitting diode microscope illumination for green fluorescent protein or fluorescein isothiocyanate epifluorescence.

Authors:  Gottfried Martin; Hansjürgen T Agostini; Lutz L Hansen
Journal:  Biotechniques       Date:  2005-02       Impact factor: 1.993

3.  Filter cubes with built-in ultrabright light-emitting diodes as exchangeable excitation light sources in fluorescence microscopy.

Authors:  C Moser; T Mayr; I Klimant
Journal:  J Microsc       Date:  2006-05       Impact factor: 1.758

4.  Calibration of a wide-field frequency-domain fluorescence lifetime microscopy system using light emitting diodes as light sources.

Authors:  A D Elder; J H Frank; J Swartling; X Dai; C F Kaminski
Journal:  J Microsc       Date:  2006-11       Impact factor: 1.758

5.  LED illumination for video-enhanced DIC imaging of single microtubules.

Authors:  Volker Bormuth; Jonathon Howard; Erik Schäffer
Journal:  J Microsc       Date:  2007-04       Impact factor: 1.758

6.  Light-emitting diodes are better illumination sources for biological microscopy than conventional sources.

Authors:  Richard W Cole; James N Turner
Journal:  Microsc Microanal       Date:  2008-03-03       Impact factor: 4.127

7.  Frequency-domain fluorescence microscopy with the LED as a light source.

Authors:  P Herman; B P Maliwal; H J Lin; J R Lakowicz
Journal:  J Microsc       Date:  2001-08       Impact factor: 1.758

  7 in total
  1 in total

1.  Open LED Illuminator: A Simple and Inexpensive LED Illuminator for Fast Multicolor Particle Tracking in Neurons.

Authors:  Jens B Bosse; Nikhila S Tanneti; Ian B Hogue; Lynn W Enquist
Journal:  PLoS One       Date:  2015-11-23       Impact factor: 3.240

  1 in total

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