| Literature DB >> 24982006 |
Vincent J Cunningham1, Christine A Parker2, Eugenii A Rabiner2, Antony D Gee2, Roger N Gunn3.
Abstract
Positron emission tomography (PET), as an in vivo pharmacological imaging tool in experimental medicine, is playing an increasing role in drug development. There are two areas where PET is particularly useful in this respect, namely biodistribution and drug occupancy studies. Radiotracer design, the properties of the molecular targets which can be studied and the quantitative estimation of pharmacological endpoints will be discussed in relation to these applications, with particular reference to studies in brain.:Year: 2005 PMID： 24982006 DOI： 10.1016/j.ddtec.2005.11.003
Source DB: PubMed Journal: Drug Discov Today Technol ISSN： 1740-6749