Literature DB >> 24981267

Discovery of therapeutic targets by phenotype-based zebrafish screens.

Randall T Peterson1.   

Abstract

The easy identification of phenotypes in the transparent zebrafish embryo has enabled numerous genetic, antisense morpholino oligonucleotide, and small molecule screens. Can zebrafish screens also be used for unbiased discovery of novel drug targets?:
© 2004 Elsevier Ltd . All rights reserved.

Entities:  

Year:  2004        PMID： 24981267     DOI： 10.1016/j.ddtec.2004.07.002

Source DB:  PubMed          Journal:  Drug Discov Today Technol        ISSN： 1740-6749


  3 in total

1.  Environmental Risk Assessment of Dexamethasone Sodium Phosphate and Tocilizumab Mixture in Zebrafish Early Life Stage (Danio rerio).

Authors:  Davide Di Paola; Jessica Maria Abbate; Carmelo Iaria; Marika Cordaro; Rosalia Crupi; Rosalba Siracusa; Ramona D'Amico; Roberta Fusco; Daniela Impellizzeri; Salvatore Cuzzocrea; Nunziacarla Spanò; Enrico Gugliandolo; Alessio Filippo Peritore
Journal:  Toxics       Date:  2022-05-25

2.  The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model.

Authors:  Jaime N Wertman; Nicole Melong; Matthew R Stoyek; Olivia Piccolo; Stewart Langley; Benno Orr; Shelby L Steele; Babak Razaghi; Jason N Berman
Journal:  Elife       Date:  2020-07-28       Impact factor: 8.140

Review 3.  Orthogonal Drug Pooling Enhances Phenotype-Based Discovery of Ocular Antiangiogenic Drugs in Zebrafish Larvae.

Authors:  Nils Ohnesorge; Temitope Sasore; Daniel Hillary; Yolanda Alvarez; Michelle Carey; Breandán N Kennedy
Journal:  Front Pharmacol       Date:  2019-05-24       Impact factor: 5.810
  3 in total

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