Literature DB >> 24979220

Steroidal esters from Ferula sinkiangensis.

Guangzhi Li1, Xiaojin Li2, Li Cao1, Liangang Shen1, Jun Zhu2, Jing Zhang1, Junchi Wang1, Lijing Zhang1, Jianyong Si3.   

Abstract

Two new steroidal esters with an unusual framework, Sinkiangenorin A and B, a new organic acid glycoside, Sinkiangenorin C, and four known lignin compounds were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds were established by spectroscopic analysis and single-crystal X-ray diffraction. All of the isolated compounds were tested against Hela, K562 and AGS human cancer cell lines. Sinkiangenorin C showed cytotoxic activity against AGS cells with an IC50 of 36.9 μM.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Arctigenin (PubChem CID: 64981); Cytotoxic activities; Ferula sinkiangensis; Lariciresinol (PubChem CID: 332427); Lignin compounds; Matairesinol (PubChem CID: 119205); Organic acid glycoside; Secroisolariciresinol (PubChem CID: 6336781); Steroidal esters

Mesh:

Substances:

Year:  2014        PMID: 24979220     DOI: 10.1016/j.fitote.2014.06.016

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  2 in total

1.  Racemic Norlignans as Diastereoisomers from Ferula sinkiangensis Resins with Antitumor and Wound-Healing Promotion Activities.

Authors:  Ying-Shi Li; Bao-Chen Yang; Shu-Min Zheng; Yong-Xian Cheng; Hong-Hua Cui
Journal:  Molecules       Date:  2022-06-17       Impact factor: 4.927

2.  A new terpene coumarin microbial transformed by Mucor polymorphosporus induces apoptosis of human gastric cancer cell line MGC-803.

Authors:  Guangzhi Li; Junchi Wang; Xiaojin Li; Jianguo Xu; Zhao Zhang; Jianyong Si
Journal:  Arch Pharm Res       Date:  2018-04-04       Impact factor: 4.946

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.