Literature DB >> 24978850

Review of the management of ovarian endometriosis: paradigm shift towards conservative approaches.

Dimitrios Psaroudakis1, Martin Hirsch, Colin Davis.   

Abstract

PURPOSE OF REVIEW: To describe the current consensus regarding the modern management of ovarian endometriosis and summarize the recent evidence that led to a shift in the management recommendations. RECENT
FINDINGS: The vast majority of the recent studies demonstrate an adverse effect of surgery on ovarian reserve markers, whereas convincing evidence of a benefit of surgery on fertility outcomes is lacking. Current research is focussing on identifying the optimal surgical technique that affords minimal injury to ovarian function. New medical treatment options in the form of aromatase inhibitors are emerging, whereas the evidence for a role of ultrasound-guided drainage and sclerotherapy is scarce and unconvincing.
SUMMARY: Consensus from Europe and the USA is for a conservative approach to the treatment of ovarian endometriosis, with early recourse to assisted reproductive technology for subfertility. Surgery is currently only being advised for severe pain or difficult access to growing follicles and only after careful counselling regarding the potential adverse effect on ovarian reserve. Research has still not identified the optimal technique for treating ovarian endometriosis. Laparoscopic ovarian cystectomy not only offers the lowest risk of recurrence and the highest chance of spontaneous pregnancy rate, but also risks significant injury to ovarian function. Medical treatment offers temporary symptom relief but does not improve the fertility outcomes, and the role of ultrasound-guided drainage remains to be established.

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Year:  2014        PMID: 24978850     DOI: 10.1097/GCO.0000000000000078

Source DB:  PubMed          Journal:  Curr Opin Obstet Gynecol        ISSN: 1040-872X            Impact factor:   1.927


  5 in total

1.  Chinese medicinal plants for advanced endometriosis after conservative surgery: a prospective, multi-center and controlled trial.

Authors:  Qing Weng; Zhi-Ming Ding; Xiang-Lin Lv; Dong-Xia Yang; Yao-Zhen Song; Fang-Fang Wang; Ying-Hui Ye; Fan Qu
Journal:  Int J Clin Exp Med       Date:  2015-07-15

2.  Expression of MMIF, HIF-1α and VEGF in Serum and Endometrial Tissues of Patients with Endometriosis.

Authors:  Fan Zhang; Xiao-Ling Liu; Wan Wang; Hong-Ling Dong; Yu-Fang Xia; Li-Ping Ruan; Li-Ping Liu
Journal:  Curr Med Sci       Date:  2018-06-22

3.  The impact of previous ovarian surgery on ovarian reserve in patients with endometriosis.

Authors:  Hsin-Ju Chiang; Pin-Yao Lin; Fu-Jen Huang; Fu-Tsai Kung; Yu-Ju Lin; Pei-Hsun Sung; Kuo-Chung Lan
Journal:  BMC Womens Health       Date:  2015-09-10       Impact factor: 2.809

4.  Aspiration versus retention ultrasound-guided ethanol sclerotherapy for treating endometrioma: A retrospective cross-sectional study.

Authors:  Abbas Aflatoonian; Nasim Tabibnejad
Journal:  Int J Reprod Biomed       Date:  2020-11-22

5.  Assisted reproductive technique outcomes in patients with endometrioma undergoing sclerotherapy vs laparoscopic cystectomy: Prospective cross-sectional study.

Authors:  Saeed Alborzi; Elham Askary; Pegah Keramati; Shaghayegh Moradi Alamdarloo; Tahereh Poordast; Mohammad Ali Ashraf; Zahra Shomali; Behieh Namavar Jahromi; Ziba Zahiri Sorouri
Journal:  Reprod Med Biol       Date:  2021-05-05
  5 in total

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