Literature DB >> 24976477

Current and future perspectives on drug-eluting bioresorbable coronary scaffolds.

Alfonso Ielasi1, Maurizio Tespili.   

Abstract

Despite improvements in stent platform, polymer and drug elution, the permanent metallic stents have significant limitations as they distort vessel physiology, predispose to late thrombosis and may preclude surgical revascularization. Bioresorbable scaffold (BRS) technology has evolved over the last few years to overcome these drawbacks. Actually, different BRS are either available or under clinical and preclinical investigation. However, the use of BRS has largely been restricted to patients recruited into clinical trials with a relatively small number of 'real world' patients treated with these devices. Here, we highlight the potentialities of these devices, describe the evidence from the recent clinical trials and discuss the potential advantages, as well as challenges, that this novel technology may face in routine clinical practice.

Entities:  

Keywords:  bioresorbable scaffolds; coronary angioplasty; drug-eluting stents

Mesh:

Year:  2014        PMID: 24976477     DOI: 10.2217/fca.14.14

Source DB:  PubMed          Journal:  Future Cardiol        ISSN: 1479-6678


  1 in total

1.  Bioresorbable vascular stents and drug-eluting stents in treatment of coronary heart disease: a meta-analysis.

Authors:  Le Ni; Hao Chen; Zhurong Luo; Yunqiang Yu
Journal:  J Cardiothorac Surg       Date:  2020-01-28       Impact factor: 1.637

  1 in total

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