Literature DB >> 24975706

Current trends in dextranomer hyaluronic acid copolymer (Deflux) injection technique for endoscopic treatment of vesicoureteral reflux.

Andrew J Kirsch1, Angela M Arlen2, Goran Lackgren3.   

Abstract

OBJECTIVE: To determine the current preferred injection technique(s) for endoscopic management of pediatric vesicoureteral reflux (VUR). Since the approval of dextranomer hyaluronic acid copolymer (Dx/HA) in 2001, injection methods have evolved and now include the hydrodistention implantation technique (HIT) and double HIT as well as subureteral transurethral injection (STING) method.
METHODS: In July 2012, 278 pediatric urologists in the United States were contacted to complete a 15-question survey regarding Dx/HA injection technique(s) currently used in their practice.
RESULTS: Fifty board-certified pediatric urologists completed the survey for a response rate of 18%. Most respondents (60%) were in a single-specialty group practice, and 12% were affiliated with an academic- or university-based practice. Respondents reported seeing a mean of 159 pediatric patients (range, 40-400 patients) with VUR annually, and 94% used Dx/HA ≥4 times in the past year. Forty-seven respondents (94%) reported using double HIT over the course of their career compared with 36 (72%) for STING and 30 (60%) for HIT (P <.05). Double HIT gained widespread acceptance between 2007 and 2008, paralleled by a decline in use of other injection techniques. A significantly higher percentage currently perform double HIT (92%) compared with either STING (24%) or HIT (34%; P <.001). Respondents reported the use of double HIT 15 times more often than STING technique and 5 times more often than HIT during the past 12 months (P <.001).
CONCLUSION: The double HIT method is currently the most commonly performed technique for endoscopic correction of VUR by pediatric urologists in the United States.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2014        PMID: 24975706     DOI: 10.1016/j.urology.2014.04.032

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  5 in total

1.  Mid-Term Safety and Efficacy of the Modified Double Hydrodistention Implantation Technique (HIT), Termed Systematic Multi-Site HIT (SMHIT), for Patients with Primary Vesicoureteral Reflux.

Authors:  Shigeru Nakamura; Kazuya Tanabe; Taiju Hyuga; Taro Kubo; Satoru Inoguchi; Shina Kawai; Hideo Nakai
Journal:  Res Rep Urol       Date:  2020-10-28

2.  Ureteric patency after Deflux® injection for the treatment of vesicoureteric reflux in children confirmed by a novel epidural catheter-assisted endoscopic technique.

Authors:  Manabu Okawada; Soichi Shibuya; Takashi Doi; Go Miyano; Hiroyuki Koga; Geoffrey J Lane; Tadaharu Okazaki; Atsuyuki Yamataka
Journal:  Pediatr Surg Int       Date:  2015-08-19       Impact factor: 1.827

Review 3.  Endoscopic injection therapy.

Authors:  Sang Woon Kim; Yong Seung Lee; Sang Won Han
Journal:  Investig Clin Urol       Date:  2017-06-02

4.  Long-Term Clinical Outcomes and Parental Satisfaction After Dextranomer/Hyaluronic Acid (Dx/HA) Injection for Primary Vesicoureteral Reflux.

Authors:  Michelle Lightfoot; Aylin N Bilgutay; Noah Tollin; Scott Eisenberg; Jake Weiser; Leah Bryan; Edwin Smith; James Elmore; Hal Scherz; Andrew J Kirsch
Journal:  Front Pediatr       Date:  2019-09-27       Impact factor: 3.418

5.  Endoscopic correction of vesicoureteral reflux in children using polyacrylate-polyalcohol copolymer (Vantris): 5-years of prospective follow-up.

Authors:  Stanisław Warchoł; Grażyna Krzemień; Agnieszka Szmigielska; Przemysław Bombiński; Krzysztof Toth; Teresa Dudek-Warchoł
Journal:  Cent European J Urol       Date:  2017-07-24
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.