Iva Hojsak1, Ana M Pavić, Sanja Kolaček. 1. Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, Zagreb, Croatia, ivahojsak@gmail.com.
Abstract
BACKGROUND: There are reports on mesalamine-induced bloody diarrhea mimicking ulcerative colitis (UC) relapse, mostly in adults. METHODS: Herein we present a case of a child with UC who developed relapse of hemorrhagic colitis related to mesalamine. RESULTS: A 10-year-old girl developed severe symptoms mimicking UC relapse 3 weeks after introduction of mesalamine therapy. After mesalamine was withdrawn, her symptoms improved, but deteriorated again during the challenge of mesalamine despite concomitant use of corticosteroids. CONCLUSION: This is the first case report on such a young child during the concomitant use of corticosteroids.
BACKGROUND: There are reports on mesalamine-induced bloody diarrhea mimicking ulcerative colitis (UC) relapse, mostly in adults. METHODS: Herein we present a case of a child with UC who developed relapse of hemorrhagic colitis related to mesalamine. RESULTS: A 10-year-old girl developed severe symptoms mimicking UC relapse 3 weeks after introduction of mesalamine therapy. After mesalamine was withdrawn, her symptoms improved, but deteriorated again during the challenge of mesalamine despite concomitant use of corticosteroids. CONCLUSION: This is the first case report on such a young child during the concomitant use of corticosteroids.
Authors: Dan Turner; Arie Levine; Johanna C Escher; Anne M Griffiths; Richard K Russell; Axel Dignass; Jorge Amil Dias; Jiri Bronsky; Christian P Braegger; Salvatore Cucchiara; Lissy de Ridder; Ulrika L Fagerberg; Séamus Hussey; Jean-Pierre Hugot; Sanja Kolacek; Kaija Leena Kolho; Paolo Lionetti; Anders Paerregaard; Alexander Potapov; Risto Rintala; Daniela E Serban; Annamaria Staiano; Brian Sweeny; Gigi Veerman; Gabor Veres; David C Wilson; Frank M Ruemmele Journal: J Pediatr Gastroenterol Nutr Date: 2012-09 Impact factor: 2.839