Literature DB >> 24973263

Magnesium should be given to all children presenting to hospital with acute severe asthma.

Mon Ohn1, Stephen Jacobe2.   

Abstract

Asthma is one of the most prevalent chronic condition affecting children worldwide and acute exacerbations requiring emergency medical management are common. In addition to corticosteroids, a number of drugs may be used in the management of acute severe asthma aiming to reverse bronchoconstriction. Magnesium sulphate - either inhaled or intravenous - may be added to conventional therapy of children with acute severe asthma. Despite its safety profile and effectiveness, the use of magnesium sulphate has been inconsistent due to lack of consensus. The authors believe that the accumulating evidence of a favorable 'cost benefit' profile justifies the use of magnesium for all children presenting with acute severe asthma.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Acute severe asthma; children; magnesium sulphate; status asthmaticus; treatment

Mesh:

Substances:

Year:  2014        PMID: 24973263     DOI: 10.1016/j.prrv.2014.05.004

Source DB:  PubMed          Journal:  Paediatr Respir Rev        ISSN: 1526-0542            Impact factor:   2.726


  7 in total

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Review 6.  Stating the obvious: intravenous magnesium sulphate should be the first parenteral bronchodilator in paediatric asthma exacerbations unresponsive to first-line therapy.

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  7 in total

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