Literature DB >> 24972639

Advanced diagnostic bronchoscopy using conscious sedation and the laryngeal nerve block: tolerability, thoroughness, and diagnostic yield.

Geetinder Goyal1, Margaret A Pisani, Terrence E Murphy, Katy L Araujo, Jonathan T Puchalski.   

Abstract

PURPOSE: Although bronchoscopy has conventionally been performed using conscious sedation, advanced diagnostic techniques like endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), peripheral EBUS, and electromagnetic navigational bronchoscopy add to procedural complexity. The adaptation of these techniques by bronchoscopists of varied backgrounds is expanding. It is not clear how patients will tolerate these advanced procedures when they are performed using traditional conscious sedation.
METHODS: We prospectively studied patients that underwent diagnostic bronchoscopic procedures using conscious sedation over a 1-year period. The primary outcome was patient tolerability measured with four questions soliciting subjective responses. Secondary outcomes included required dosage of medications, thoroughness of the procedure, diagnostic yield, and occurrence of complications.
RESULTS: A total of 181 patients were enrolled. Compared to patients in whom conventional bronchoscopy with transbronchial biopsies were performed, there was no difference in patient tolerability using the advanced techniques. Although some of the advanced procedures added to the procedure time, the required amount of medication was within commonly accepted dosages. When EBUS-TBNA was performed, a mean of 2.8 lymph node stations per patient were sampled. A specific diagnosis was obtained in 55.9 % of patients who solely underwent EBUS-TBNA. The diagnostic yield increased to 75.7 % when a parenchymal abnormality prompted additional biopsies. One patient required sedation reversal. Complications were minimal.
CONCLUSIONS: This study suggests that advanced diagnostic bronchoscopic procedures are well tolerated using conscious sedation with no compromise of thoroughness, diagnostic yield, or safety. This may be useful for bronchoscopists using these techniques who do not have ready access to general anesthesia.

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Year:  2014        PMID: 24972639      PMCID: PMC5417331          DOI: 10.1007/s00408-014-9607-4

Source DB:  PubMed          Journal:  Lung        ISSN: 0341-2040            Impact factor:   2.584


  18 in total

1.  Patient satisfaction with bronchoscopy.

Authors:  Noah Lechtzin; Haya R Rubin; Peter White; Mollie Jenckes; Gregory B Diette
Journal:  Am J Respir Crit Care Med       Date:  2002-07-19       Impact factor: 21.405

2.  Trainee impact on procedural complications: an analysis of 967 consecutive flexible bronchoscopy procedures in an interventional pulmonology practice.

Authors:  David R Stather; Paul MacEachern; Alex Chee; Elaine Dumoulin; Alain Tremblay
Journal:  Respiration       Date:  2013-03-12       Impact factor: 3.580

3.  Endobronchial ultrasound guided transbronchial needle aspiration for staging of lung cancer.

Authors:  Kazuhiro Yasufuku; Masako Chiyo; Eitetsu Koh; Yasumitsu Moriya; Akira Iyoda; Yasuo Sekine; Kiyoshi Shibuya; Toshihiko Iizasa; Takehiko Fujisawa
Journal:  Lung Cancer       Date:  2005-09-19       Impact factor: 5.705

4.  American College of Chest Physicians consensus statement on the use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy in adult patients.

Authors:  Momen M Wahidi; Prasoon Jain; Michael Jantz; Pyng Lee; G Burkhard Mackensen; Sally Y Barbour; Carla Lamb; Gerard A Silvestri
Journal:  Chest       Date:  2011-11       Impact factor: 9.410

Review 5.  Radial probe endobronchial ultrasound for the diagnosis of peripheral lung cancer: systematic review and meta-analysis.

Authors:  D P Steinfort; Y H Khor; R L Manser; L B Irving
Journal:  Eur Respir J       Date:  2010-08-06       Impact factor: 16.671

6.  Diagnosis of lung nodules with peripheral/radial endobronchial ultrasound-guided transbronchial biopsy.

Authors:  David W Hsia; Kurt W Jensen; Douglas Curran-Everett; Ali I Musani
Journal:  J Bronchology Interv Pulmonol       Date:  2012-01

7.  Comparison of moderate versus deep sedation for endobronchial ultrasound transbronchial needle aspiration.

Authors:  Lonny B Yarmus; Jason A Akulian; Christopher Gilbert; Stephen C Mathai; Srividya Sathiyamoorthy; Sarina Sahetya; Kassem Harris; Colin Gillespie; Andrew Haas; David Feller-Kopman; Daniel Sterman; Hans J Lee
Journal:  Ann Am Thorac Soc       Date:  2013-04

8.  Diagnosis of mediastinal adenopathy-real-time endobronchial ultrasound guided needle aspiration versus mediastinoscopy.

Authors:  Armin Ernst; Devanand Anantham; Ralf Eberhardt; Mark Krasnik; Felix J F Herth
Journal:  J Thorac Oncol       Date:  2008-06       Impact factor: 15.609

9.  Complications, consequences, and practice patterns of endobronchial ultrasound-guided transbronchial needle aspiration: Results of the AQuIRE registry.

Authors:  George A Eapen; Archan M Shah; Xiudong Lei; Carlos A Jimenez; Rodolfo C Morice; Lonny Yarmus; Joshua Filner; Cynthia Ray; Gaetane Michaud; Sara R Greenhill; Mona Sarkiss; Roberto Casal; David Rice; David E Ost
Journal:  Chest       Date:  2013-04       Impact factor: 9.410

10.  Endobronchial ultrasound-guided transbronchial needle aspiration prevents mediastinoscopies in the diagnosis of isolated mediastinal lymphadenopathy: a prospective trial.

Authors:  Neal Navani; David R Lawrence; Shyam Kolvekar; Martin Hayward; Dorcas McAsey; Gabrijela Kocjan; Mary Falzon; Arrigo Capitanio; Penny Shaw; Stephen Morris; Rumana Z Omar; Sam M Janes
Journal:  Am J Respir Crit Care Med       Date:  2012-05-31       Impact factor: 21.405

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  5 in total

1.  Endobronchial Ultrasound-Guided Cautery-Assisted Transbronchial Forceps Biopsies: Safety and Sensitivity Relative to Transbronchial Needle Aspiration.

Authors:  Kyle Bramley; Margaret A Pisani; Terrence E Murphy; Katy L Araujo; Robert J Homer; Jonathan T Puchalski
Journal:  Ann Thorac Surg       Date:  2016-02-22       Impact factor: 4.330

2.  A Retrospective Analysis of Respiratory Complications under General Anesthesia during EBUS-TBNA.

Authors:  Emily A S Bergbower; Caron Hong; Miranda Gibbons; Ashutosh Sachdeva; Peter Rock; Megan G Anders
Journal:  J Community Hosp Intern Med Perspect       Date:  2022-01-31

Review 3.  The role of sedation in endobronchial ultrasound-guided transbronchial needle aspiration: Systematic review.

Authors:  Pantaree Aswanetmanee; Chok Limsuwat; Mohamad Kabach; Abdul Hamid Alraiyes; Fayez Kheir
Journal:  Endosc Ultrasound       Date:  2016 Sep-Oct       Impact factor: 5.628

4.  Efficacy and safety of EBUS-TBNA under conscious sedation with meperidine and midazolam.

Authors:  Roberto Piro; Eleonora Casalini; Matteo Fontana; Carla Galeone; Patrizia Ruggiero; Sofia Taddei; Giulia Ghidoni; Giulia Patricelli; Nicola Facciolongo
Journal:  Thorac Cancer       Date:  2022-01-07       Impact factor: 3.500

5.  1% versus 2% lignocaine for airway anesthesia in endobronchial ultrasound-guided transbronchial needle aspiration: A pilot, double-blind, randomized controlled trial.

Authors:  Shiba Kalyan Biswal; Saurabh Mittal; Vijay Hadda; Anant Mohan; Gopi C Khilnani; Ravindra M Pandey; Randeep Guleria; Karan Madan
Journal:  Lung India       Date:  2018 Nov-Dec
  5 in total

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