Amanda S Trudell1, Judette M Louis2, Methodius G Tuuli1, Aaron B Caughey3, Anthony O Odibo1, Alison G Cahill1. 1. Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri. 2. Department of Obstetrics and Gynecology, University of South Florida, Tampa, Florida. 3. Department of Obstetrics and Gynecology, Oregon Health and Sciences University, Portland, Oregon.
Abstract
OBJECTIVE: Obstructive sleep apnea (OSA) is a risk factor for adverse perinatal outcomes. We aimed to test the hypothesis that maternal Mallampati class (MC), as a marker for OSA, is associated with adverse perinatal outcomes. STUDY DESIGN: We performed a retrospective secondary analysis of a prospective cohort of term births (≥ 37 weeks). Fetal anomalies and aneuploidy were excluded. Primary outcome was small for gestational age (SGA). Secondary outcomes included preeclampsia, neonatal cord arterial blood gas pH < 7.10 and < 7.05, base excess < - 8 and < - 12 mEq/L. Outcomes were compared between mothers with low MC airways and high MC airways using logistic regression. RESULTS: A total of 1,823 women met the inclusion criteria. No significant differences were found in the risk of SGA (adjusted odds ratio [aOR] 0.9, 95% confidence interval [CI] 0.6-1.2), preeclampsia (aOR 1.2, 95% CI 0.8-1.9) or neonatal acidemia (aOR 0.8, 95% CI 0.3-2.0), between high and low MC. CONCLUSION: High MC is not associated with adverse perinatal outcomes. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
OBJECTIVE:Obstructive sleep apnea (OSA) is a risk factor for adverse perinatal outcomes. We aimed to test the hypothesis that maternal Mallampati class (MC), as a marker for OSA, is associated with adverse perinatal outcomes. STUDY DESIGN: We performed a retrospective secondary analysis of a prospective cohort of term births (≥ 37 weeks). Fetal anomalies and aneuploidy were excluded. Primary outcome was small for gestational age (SGA). Secondary outcomes included preeclampsia, neonatal cord arterial blood gas pH < 7.10 and < 7.05, base excess < - 8 and < - 12 mEq/L. Outcomes were compared between mothers with low MC airways and high MC airways using logistic regression. RESULTS: A total of 1,823 women met the inclusion criteria. No significant differences were found in the risk of SGA (adjusted odds ratio [aOR] 0.9, 95% confidence interval [CI] 0.6-1.2), preeclampsia (aOR 1.2, 95% CI 0.8-1.9) or neonatal acidemia (aOR 0.8, 95% CI 0.3-2.0), between high and low MC. CONCLUSION: High MC is not associated with adverse perinatal outcomes. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Authors: Michael Friedman; Craig Hamilton; Christian G Samuelson; Mary E Lundgren; Thomas Pott Journal: Otolaryngol Head Neck Surg Date: 2013-01-15 Impact factor: 3.497