Literature DB >> 24968714

Using tramadol to measure CYP2D6 metabolism in critically ill adults.

Katie Lane1, John J Dixon, Denise McKeown, Atholl Johnston, Ron H N van Schaik, Marianne van Fessem, Iain A M MacPhee, Barbara J Philips.   

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Year:  2014        PMID： 24968714     DOI： 10.1007/s00134-014-3372-y

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN： 0342-4642            Impact factor:   17.440


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  5 in total

1.  Acute kidney injury reduces the hepatic metabolism of midazolam in critically ill patients.

Authors:  C J Kirwan; I A M MacPhee; T Lee; D W Holt; B J Philips
Journal:  Intensive Care Med       Date:  2011-10-18       Impact factor: 17.440

2.  Concordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation.

Authors:  S M Abdel-Rahman; J S Leeder; J T Wilson; A Gaedigk; R R Gotschall; R Medve; S Liao; S P Spielberg; G L Kearns
Journal:  J Clin Pharmacol       Date:  2002-01       Impact factor: 3.126

Review 3.  Evaluation of probe drugs and pharmacokinetic metrics for CYP2D6 phenotyping.

Authors:  D Frank; U Jaehde; U Fuhr
Journal:  Eur J Clin Pharmacol       Date:  2007-02-02       Impact factor: 2.953

4.  In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration.

Authors:  Y S Lin; G F Lockwood; M A Graham; W R Brian; C M Loi; M R Dobrinska; D D Shen; P B Watkins; G R Wilkinson; E D Kharasch; K E Thummel
Journal:  Pharmacogenetics       Date:  2001-12

5.  Using midazolam to monitor changes in hepatic drug metabolism in critically ill patients.

Authors:  Christopher John Kirwan; Terry Lee; David W Holt; R Michael Grounds; Iain A M MacPhee; Barbara J Philips
Journal:  Intensive Care Med       Date:  2009-02-07       Impact factor: 17.440
  5 in total

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