Guillermo Ortíz1, Carmelo Dueñas2, Ferney Rodríguez3, Lena Barrera4, Gisela de La Rosa5, Rodolfo Dennis6, Marcela Granados7, Darío Londoño8, Francisco Molina9, Fabián Jaimes10. 1. Departamento de Cuidado Intensivo, Hospital Santa Clara, Bogotá, D.C, Colombia. 2. Departamento de Cuidado Intensivo, Hospital Bocagrande, Cartagena, Colombia. 3. Departamento de Medicina Interna, Universidad de Antioquia, Medellín, Colombia. 4. Departamento de Epidemiología, Universidad del Valle, Cali, Cali, Colombia. 5. Departamento de Cuidado Intensivo, Hospital Pablo Tobón Uribe, Medellín, Colombia. 6. Departamento de Medicina Interna, Fundación Cardio-Infantil, Bogotá, D.C, Colombia. 7. Departamento de Cuidado Intensivo, Fundación Valle de Lili, Cali, Cali, Colombia. 8. Departamento de Cuidado Intensivo, Pontificia Universidad Javeriana, Bogotá, D.C, Colombia. 9. Departamento de Cuidado Intensivo, Universidad Pontificia Bolivariana. 10. Departamento de Cuidado Intensivo, Universidad de Antioquia.
Abstract
INTRODUCTION: Currently, there is not enough data available concerning sepsis in developing countries, especially in Latin America. OBJECTIVE: We developed a study aimed at determining the frequency, clinical and epidemiological characteristics, and the consequences of sepsis in patients requiring admission to intensive care units in Colombia. MATERIALS AND METHODS: This was a secondary analysis of a prospective cohort study carried out over a six-month period, from September 1, 2007, to February 28, 2008, in ten medical/surgical intensive care units in four Colombian cities. Patients were considered eligible if they had a probable or confirmed diagnosis of infection according to medical records. We recorded demographic characteristics, first admission diagnosis and co-morbidities, clinical status, and sepsis, severe sepsis or septic shock. RESULTS: During the study period, 826 patients were admitted to the intensive care units. From these patients, 421 (51%) developed sepsis in the community, 361 (44%) in the ICU, and 44 (5%) during hospitalization in the general ward. Two hundred and fifty three patients (30.6%) had involvement of one organ system: 20% had respiratory involvement, followed by kidney and central nervous system involvement with 3.4% and 2.7%, respectively. CONCLUSIONS: In our cohort of septic patients, the prevalence of sepsis treated in ICU is similar to that reported in other studies, as well as the overall mortality.
INTRODUCTION: Currently, there is not enough data available concerning sepsis in developing countries, especially in Latin America. OBJECTIVE: We developed a study aimed at determining the frequency, clinical and epidemiological characteristics, and the consequences of sepsis in patients requiring admission to intensive care units in Colombia. MATERIALS AND METHODS: This was a secondary analysis of a prospective cohort study carried out over a six-month period, from September 1, 2007, to February 28, 2008, in ten medical/surgical intensive care units in four Colombian cities. Patients were considered eligible if they had a probable or confirmed diagnosis of infection according to medical records. We recorded demographic characteristics, first admission diagnosis and co-morbidities, clinical status, and sepsis, severe sepsis or septic shock. RESULTS: During the study period, 826 patients were admitted to the intensive care units. From these patients, 421 (51%) developed sepsis in the community, 361 (44%) in the ICU, and 44 (5%) during hospitalization in the general ward. Two hundred and fifty three patients (30.6%) had involvement of one organ system: 20% had respiratory involvement, followed by kidney and central nervous system involvement with 3.4% and 2.7%, respectively. CONCLUSIONS: In our cohort of septicpatients, the prevalence of sepsis treated in ICU is similar to that reported in other studies, as well as the overall mortality.
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