Literature DB >> 24966265

Stroke as the presenting feature of new onset diabetes in a young man.

Ruth Jones1, Emily McMurray2, Oliver Robinson3.   

Abstract

A 34-year-old man presented to a hospital with a 7-day history of nausea, vertigo, ataxia and frontal headache. Examination revealed ipsilateral cerebellar signs. CT of the brain demonstrated left cerebellar hypodensity suggestive of ischaemic stroke or space occupying lesion. Full blood count showed a markedly raised haemoglobin (219 g/L) and haematocrit (0.56). Admission urinalysis was performed but the results not reviewed. Owing to patient deterioration, an arterial blood gas was performed. This showed profound metabolic acidosis. Repeat urinalysis was positive for glucose and ketones. MRI of the brain confirmed ischaemic stroke. The underlying cause of this was hyperviscosity secondary to relative polycythaemia, resulting from undiagnosed diabetic ketoacidosis as a first presentation of diabetes. This case report highlights ischaemic stroke as an unusual presenting feature of diabetic ketoacidosis. Notably, the underlying diagnosis of diabetic ketoacidosis was initially missed, thereby emphasising the importance of performing an admission urinalysis and acting on the results. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 24966265      PMCID: PMC4078437          DOI: 10.1136/bcr-2014-204251

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  Ketosis-prone type 2 diabetes: time to revise the classification of diabetes.

Authors:  Guillermo E Umpierrez
Journal:  Diabetes Care       Date:  2006-12       Impact factor: 19.112

2.  Simultaneous pulmonary and cerebral oedema, and multiple CNS infarctions as complications of diabetic ketoacidosis: a case report.

Authors:  A N Dixon; E B Jude; A K Banerjee; S C Bain
Journal:  Diabet Med       Date:  2006-05       Impact factor: 4.359

Review 3.  Diabetes mellitus: a hypercoagulable state.

Authors:  M E Carr
Journal:  J Diabetes Complications       Date:  2001 Jan-Feb       Impact factor: 2.852

Review 4.  Narrative review: ketosis-prone type 2 diabetes mellitus.

Authors:  Guillermo E Umpierrez; Dawn Smiley; Abbas E Kitabchi
Journal:  Ann Intern Med       Date:  2006-03-07       Impact factor: 25.391

5.  Diabetic ketoacidosis in obese African-Americans.

Authors:  G E Umpierrez; M M Casals; S P Gebhart; P S Mixon; W S Clark; L S Phillips
Journal:  Diabetes       Date:  1995-07       Impact factor: 9.461

6.  Diabetic ketoacidosis-associated stroke in children and youth.

Authors:  Jennifer Ruth Foster; Gavin Morrison; Douglas D Fraser
Journal:  Stroke Res Treat       Date:  2011-02-22
  6 in total
  1 in total

1.  Diabetic ketoacidosis, COVID-19 and blood viscosity.

Authors:  Rujittika Mungmunpuntipantip; Viroj Wiwanitkit
Journal:  J Taibah Univ Med Sci       Date:  2021-11-11
  1 in total

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