Literature DB >> 24965726

Panning for molecular gold in whipworm genomes.

Elodie Ghedin1.   

Abstract

Two new studies report genomic data on three species of whipworm, soil-transmitted parasitic worms responsible for trichuriasis. These genomes provide insights into host-pathogen interactions and potential for new drug targets for helminth therapy.

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Year:  2014        PMID： 24965726     DOI： 10.1038/ng.3018

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  15 in total

Review 1.  Geoepidemiology, gender and autoimmune disease.

Authors:  Luca Moroni; Ilaria Bianchi; Ana Lleo
Journal:  Autoimmun Rev       Date:  2011-11-28       Impact factor: 9.754

Review 2.  Rescuing the bottom billion through control of neglected tropical diseases.

Authors:  Peter J Hotez; Alan Fenwick; Lorenzo Savioli; David H Molyneux
Journal:  Lancet       Date:  2009-05-02       Impact factor: 79.321

Review 3.  Immunomodulation by helminth parasites: defining mechanisms and mediators.

Authors:  Henry J McSorley; James P Hewitson; Rick M Maizels
Journal:  Int J Parasitol       Date:  2013-01-03       Impact factor: 3.981

Review 4.  Helminth therapy (worms) for induction of remission in inflammatory bowel disease.

Authors:  Sushil K Garg; Ashley M Croft; Peter Bager
Journal:  Cochrane Database Syst Rev       Date:  2014-01-20

5.  The relationship between Trichuris trichiura (Linnaeus 1758) of man and Trichuris suis (Schrank 1788) of the pig.

Authors:  R J Beer
Journal:  Res Vet Sci       Date:  1976-01       Impact factor: 2.534

6.  IL-10 is critical for host resistance and survival during gastrointestinal helminth infection.

Authors:  Lisa R Schopf; Karl F Hoffmann; Allen W Cheever; Joseph F Urban; Thomas A Wynn
Journal:  J Immunol       Date:  2002-03-01       Impact factor: 5.422

7.  Randomised clinical trial: the safety and tolerability of Trichuris suis ova in patients with Crohn's disease.

Authors:  W J Sandborn; D E Elliott; J Weinstock; R W Summers; A Landry-Wheeler; N Silver; M D Harnett; S B Hanauer
Journal:  Aliment Pharmacol Ther       Date:  2013-06-03       Impact factor: 8.171

Review 8.  Trichuris muris: a model of gastrointestinal parasite infection.

Authors:  Joanna E Klementowicz; Mark A Travis; Richard K Grencis
Journal:  Semin Immunopathol       Date:  2012-10-11       Impact factor: 9.623

9.  Genome and transcriptome of the porcine whipworm Trichuris suis.

Authors:  Aaron R Jex; Peter Nejsum; Erich M Schwarz; Li Hu; Neil D Young; Ross S Hall; Pasi K Korhonen; Shengguang Liao; Stig Thamsborg; Jinquan Xia; Pengwei Xu; Shaowei Wang; Jean-Pierre Y Scheerlinck; Andreas Hofmann; Paul W Sternberg; Jun Wang; Robin B Gasser
Journal:  Nat Genet       Date:  2014-06-15       Impact factor: 38.330

10.  Trichuris suis ova in relapsing-remitting multiple sclerosis and clinically isolated syndrome (TRIOMS): study protocol for a randomized controlled trial.

Authors:  Berit Rosche; Klaus-Dieter Wernecke; Stephanie Ohlraun; Jan-Markus Dörr; Friedemann Paul
Journal:  Trials       Date:  2013-04-25       Impact factor: 2.279
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  1 in total

1.  A Randomised, Double-blind, Placebo-controlled Trial of Trichuris suis ova in Active Crohn's Disease.

Authors:  Jürgen Schölmerich; Klaus Fellermann; Frank W Seibold; Gerhard Rogler; Jost Langhorst; Stefanie Howaldt; Gottfried Novacek; Andreas Munk Petersen; Oliver Bachmann; Harald Matthes; Norbert Hesselbarth; Niels Teich; Jan Wehkamp; Jochen Klaus; Claudia Ott; Karin Dilger; Roland Greinwald; Ralph Mueller
Journal:  J Crohns Colitis       Date:  2017-04-01       Impact factor: 9.071
  1 in total

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