| Literature DB >> 2496563 |
P Temperani1, P Zucchini, G Emilia, S Sacchi, L Selleri, U Torelli.
Abstract
Two further cases of acquired isodicentric (X)(q13) chromosome in patients with myeloproliferative disorders are reported. One patient had a primary myelofibrosis and the other a chronic myelogenous leukemia. DNA replication study demonstrated that both abnormal X chromosomes were late replicating in all cells examined. The inactive condition of idic(X)(q13) seems to be indicative of a selective advantage for a cell carrying this alteration.Entities:
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Year: 1989 PMID： 2496563 DOI： 10.1159/000205549
Source DB: PubMed Journal: Acta Haematol ISSN： 0001-5792 Impact factor: 2.195