| Literature DB >> 24962552 |
U Hillen1, M Ulrich, M Alter, J C Becker, R Gutzmer, U Leiter, A Lonsdorf, A Messerschmidt, C Ulrich.
Abstract
The incidence of non-melanoma skin cancer (NMSC) is increasing. Squamous cell carcinoma of the skin (SCC) is a tumor of the elderly. Due to the increasing life expectancy, SCC will become more and more frequent in the future. Generally SCC has a favorable prognosis. Standard therapy is microscopically- controlled excision. Therapy of advanced and metastatic SCC is still challenging. Patients with regional lymph node metastasis have ten-year survival rates less than 20%; patients with distant metastases less than 10%. Immunosuppression has been shown to be one of the key prognostic factors for metastasis. The article reviews SCC and focusses on patients being at risk for an unfavorable course.Entities:
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Year: 2014 PMID: 24962552 DOI: 10.1007/s00105-013-2734-7
Source DB: PubMed Journal: Hautarzt ISSN: 0017-8470 Impact factor: 0.751