Literature DB >> 24961439

An algorithm for treating extracranial head and neck schwannomas.

Daniel Yafit1, Gilad Horowitz, Iosif Vital, Garrett Locketz, Dan M Fliss.   

Abstract

Surgical resection of extracranial head and neck schwannomas (ECHNS) may be associated with major morbidity, but some ECHNSs can be safely treated expectantly. The aim of this study is to present a large case series and an algorithm for therapeutic decision-making in the management of ECHNS. The clinical records of patients diagnosed and treated for ECHNS between 1999 and 2012 at The Tel Aviv Sourasky Medical Center were reviewed retrospectively. All relevant demographic and medical data were extracted, among them presenting symptoms, surgical approaches, nerve of origin, complications and follow-up. A total of 53 patients with ECHNS were included in this clinical study. There were 29 males and 24 females whose mean age was 49.2 years, and all were treated surgically. The schwannomas originated from the brachial plexus, sympathetic chain, vagus nerve, trigeminal nerve, lip, hypoglossal nerve and larynx. Intracapsular enucleation was performed in 32 (60 %) patients, and the remaining 21 (40 %) patients underwent complete excision of the tumor with the involved nerve segment. Thirty-two patients (60 %) had postoperative neurological deficits. This study provides an algorithm to serve as a guideline in the decision-making process for this patient population. Although there is abundant evidence regarding the efficacy of radiotherapy for acoustic schwannoma, the value of radiotherapy as a treatment alternative for patients with ECNHS, especially those unsuitable for surgery, has not been established and further studies are warranted.

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Mesh:

Year:  2014        PMID: 24961439     DOI: 10.1007/s00405-014-3156-6

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  18 in total

1.  Outcomes of stereotactic radiosurgery and stereotactic radiotherapy for the treatment of vestibular schwannoma.

Authors:  Winward Choy; Marko Spasic; Patrick Pezeshkian; Brendan M Fong; Daniel T Nagasawa; Andy Trang; Ishani Mathur; Antonio De Salles; Alessandra Gorgulho; Michael Selch; Quinton S Gopen; Isaac Yang
Journal:  Neurosurgery       Date:  2013-08       Impact factor: 4.654

2.  Decision analysis of treatment options for vestibular schwannoma.

Authors:  Robert G Whitmore; Christopher Urban; Ephraim Church; Michael Ruckenstein; Sherman C Stein; John Y K Lee
Journal:  J Neurosurg       Date:  2010-04-16       Impact factor: 5.115

Review 3.  Current management of head and neck schwannomas.

Authors:  Roger V Moukarbel; Alain N Sabri
Journal:  Curr Opin Otolaryngol Head Neck Surg       Date:  2005-04       Impact factor: 2.064

4.  Genetic testing and screening of individuals at risk of NF2.

Authors:  D G Evans; F L Raymond; J G Barwell; D Halliday
Journal:  Clin Genet       Date:  2011-12-16       Impact factor: 4.438

5.  Evolution in the assessment and management of trigeminal schwannoma.

Authors:  Bharat Guthikonda; Philip V Theodosopoulos; Harry van Loveren; John M Tew; Myles L Pensak
Journal:  Laryngoscope       Date:  2008-02       Impact factor: 3.325

6.  Neck nerve trunks schwannomas: clinical features and postoperative neurologic outcome.

Authors:  Carlos Eugenio Nabuco de Araujo; Daniel M Ramos; Raquel A Moyses; Marcelo D Durazzo; Cláudio R Cernea; Alberto R Ferraz
Journal:  Laryngoscope       Date:  2008-09       Impact factor: 3.325

7.  Vestibular schwannoma: surgery or gamma knife radiosurgery? A prospective, nonrandomized study.

Authors:  Erling Myrseth; Per Møller; Paal-Henning Pedersen; Morten Lund-Johansen
Journal:  Neurosurgery       Date:  2009-04       Impact factor: 4.654

8.  Fractionated stereotactic radiotherapy for acoustic neuromas: long-term outcomes.

Authors:  D K Woolf; M Williams; C L Goh; D R Henderson; R V Menashy; N Simpson; B Mastroianni; C H Collis
Journal:  Clin Oncol (R Coll Radiol)       Date:  2013-08-22       Impact factor: 4.126

9.  What intervention is best practice for vestibular schwannomas? A systematic review of controlled studies.

Authors:  John G Wolbers; Alof Hg Dallenga; Alejandra Mendez Romero; Anne van Linge
Journal:  BMJ Open       Date:  2013-02-22       Impact factor: 2.692

10.  Diagnosis and management of extracranial head and neck schwannomas: a review of 27 cases.

Authors:  Ryuji Yasumatsu; Torahiko Nakashima; Rina Miyazaki; Yuichi Segawa; Shizuo Komune
Journal:  Int J Otolaryngol       Date:  2013-05-08
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  5 in total

1.  Submandibular schwannoma: is excision a 'gold standard treatment'?

Authors:  Sarah Siaki Loterh; Vinod Prabhu; Ciaran O'Brien
Journal:  BMJ Case Rep       Date:  2015-08-13

2.  Schwannoma of the long thoracic nerve in the left axilla: a case report.

Authors:  Jia Tian; Qishun Huang; Zhenbing Chen
Journal:  J Int Med Res       Date:  2019-12-04       Impact factor: 1.671

3.  Cervical schwannoma with acute worsening and intratumoral hemorrhage.

Authors:  Uma V Mahajan; Mohit Patel; Alia M Hdeib
Journal:  Surg Neurol Int       Date:  2021-08-16

4.  Extracranial non-vestibular head and neck schwannomas.

Authors:  Baoxin Wang; Junjie Yuan; Xinwei Chen; Hongming Xu; Yuan Zhou; Pin Dong
Journal:  Saudi Med J       Date:  2015-11       Impact factor: 1.484

5.  Supraclavicular Cervical Schwannoma: A Case Report.

Authors:  Mohammed Elkarim Mohammed; Abdullatif Khan; Mohammed Asiri
Journal:  Cureus       Date:  2019-10-16
  5 in total

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