| Literature DB >> 24959489 |
Manu Dhillon1, Divya Tomar2, Manu Sharma3, Samta Goel4, Siddharth Srivastava1.
Abstract
Pleomorphic adenoma originally called the mixed tumour is a neoplasm commonly involving major salivary glands. The spectrum of malignancy in pleomorphic adenoma comprises three distinct entities - Carcinoma ex pleomorphic adenoma, carcinosarcoma and benign metastasising pleomorphic adenoma. Carcinoma ex pleomorphic adenoma consists of pleomorphic adenoma with a malignant epithelial component. Occasionally, carcinomas ex pleomorphic adenoma develops metastasis. Here we are reporting here a case of benign pleomorphic adenoma arising in parotid gland which turned into malignancy after four years. The patient developed facial nerve paralysis suggesting malignant transformation. Along the course of the disease, the patient developed regional metastasis to lymph nodes and neck and distant metastasis to liver. This case report emphasises the role of advanced imaging modalities in the early diagnosis of the condition and evaluation of metastasis. The patients with this condition should be treated early for favorable outcome and investigated for distant metastasis.Entities:
Keywords: Malignancy; Mixed tumour; Pleomorphic adenoma; Salivary glands
Year: 2014 PMID: 24959489 PMCID: PMC4064897 DOI: 10.7860/JCDR/2014/8041.4248
Source DB: PubMed Journal: J Clin Diagn Res ISSN: 0973-709X