Literature DB >> 24959489

Carcinoma ex pleomorphic adenoma of parotid gland with hepatic metastasis: clinic-radiological case report.

Manu Dhillon1, Divya Tomar2, Manu Sharma3, Samta Goel4, Siddharth Srivastava1.   

Abstract

Pleomorphic adenoma originally called the mixed tumour is a neoplasm commonly involving major salivary glands. The spectrum of malignancy in pleomorphic adenoma comprises three distinct entities - Carcinoma ex pleomorphic adenoma, carcinosarcoma and benign metastasising pleomorphic adenoma. Carcinoma ex pleomorphic adenoma consists of pleomorphic adenoma with a malignant epithelial component. Occasionally, carcinomas ex pleomorphic adenoma develops metastasis. Here we are reporting here a case of benign pleomorphic adenoma arising in parotid gland which turned into malignancy after four years. The patient developed facial nerve paralysis suggesting malignant transformation. Along the course of the disease, the patient developed regional metastasis to lymph nodes and neck and distant metastasis to liver. This case report emphasises the role of advanced imaging modalities in the early diagnosis of the condition and evaluation of metastasis. The patients with this condition should be treated early for favorable outcome and investigated for distant metastasis.

Entities:  

Keywords:  Malignancy; Mixed tumour; Pleomorphic adenoma; Salivary glands

Year:  2014        PMID: 24959489      PMCID: PMC4064897          DOI: 10.7860/JCDR/2014/8041.4248

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  7 in total

1.  Carcinoma ex pleomorphic adenoma of soft palate with cavernous sinus invasion.

Authors:  Hsuan-Ho Chen; Li-Yu Lee; Shy-Chyi Chin; I-How Chen; Chun-Ta Liao; Shiang-Fu Huang
Journal:  World J Surg Oncol       Date:  2010-03-30       Impact factor: 2.754

2.  CNS metastases of carcinoma ex pleomorphic adenoma of the parotid gland.

Authors:  S P Sheedy; K M Welker; D R DeLone; J R Gilbertson
Journal:  AJNR Am J Neuroradiol       Date:  2006-08       Impact factor: 3.825

Review 3.  An update on grading of salivary gland carcinomas.

Authors:  Raja R Seethala
Journal:  Head Neck Pathol       Date:  2009-02-25

4.  Carcinoma ex pleomorphic adenoma of the parotid gland: radiologic-pathologic correlation with MR imaging including diffusion-weighted imaging.

Authors:  H Kato; M Kanematsu; K Mizuta; Y Ito; Y Hirose
Journal:  AJNR Am J Neuroradiol       Date:  2008-02-13       Impact factor: 3.825

5.  Carcinoma ex pleomorphic adenoma of the minor salivary gland with pulmonary metastasis.

Authors:  Hüseyin Akan; Levent Yildiz; Recep Unal
Journal:  Diagn Interv Radiol       Date:  2008-03       Impact factor: 2.630

6.  Spectrum of malignancy in mixed tumors of salivary gland: a morphological and immunohistochemical review of 23 cases.

Authors:  Asim Qureshi; Abrar Barakzai; Najam Ul Sahar; Rubina Gulzar; Zubair Ahmad; Sheema H Hassan
Journal:  Indian J Pathol Microbiol       Date:  2009 Apr-Jun       Impact factor: 0.740

7.  Adenoid cystic carcinoma ex pleomorphic adenoma of the parotid gland.

Authors:  Fumio Ide; Kenji Mishima; Hiroyuki Yamada; Ichiro Saito
Journal:  Head Neck Pathol       Date:  2009-02-28
  7 in total
  2 in total

1.  Carcinoma ex pleomorphic adenoma of major salivary glands: CT and MR imaging findings.

Authors:  Can Wang; Qiang Yu; Siyi Li; Jingjing Sun; Ling Zhu; Pingzhong Wang
Journal:  Dentomaxillofac Radiol       Date:  2021-06-23       Impact factor: 3.525

2.  Pineal and leptomeningeal metastases from a parotid carcinoma ex pleomorphic adenoma.

Authors:  Olivia Francies; Dimitrios Paraskevopoulos; Ganesalingam Narenthiran; Kim Piper; Amen Sibtain; Curtis Offiah; Anant S Krishnan
Journal:  BJR Case Rep       Date:  2016-01-19
  2 in total

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