| Literature DB >> 24959488 |
Sunitha Susan Varghese1, Patricia Sebastian1, Vivek Joseph2, Geeta Chacko3, Selvamani Backianathan4.
Abstract
Primary glioblastoma of spinal cord are rare and are associated with poor survival especially in adults. We report a case of glioblastoma of thoracic spinal cord (D3 to D6) in an adult treated with partial resection surgery and radiation therapy with a survival of six years with good quality of life. The patient had paraplegia at presentation but improved after surgery and radiation therapy to grade 4 in both lower limbs. After 5 years, he developed new lesion in a different location of the spine (L1, L2 & L5) along with multiple lesions over entire spine and was treated with radiation therapy and a year later developed a new lesion intracranially in the posterior fossa involving cerebellopontine angle region infiltrating brainstem. He was treated with palliative radiotherapy and is on chemotherapy with Temozolomide and is still alive with ability to do activities of daily living at the time of this report. Radiation therapy provided prolonged local control with effective palliation of symptoms and good quality of life in this patient enabling to do activities of daily living.Entities:
Keywords: Glioblastoma; Spinal cord; Survival
Year: 2014 PMID: 24959488 PMCID: PMC4064906 DOI: 10.7860/JCDR/2014/8486.4218
Source DB: PubMed Journal: J Clin Diagn Res ISSN: 0973-709X