Literature DB >> 24958974

Umeclidinium bromide and vilanterol trifenatate inhalation powder.

Dennis J Cada1, Kyle Ingram2, James Leonard3, Danial E Baker4.   

Abstract

Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation/medication use evaluation (DUE/MUE) is also provided each month. With a subscription, the monographs are sent in print and are also available on-line. Monographs can be customized to meet the needs of a facility. A drug class review is now published monthly with The Formulary Monograph Service. Through the cooperation of The Formulary, Hospital Pharmacy publishes selected reviews in this column. For more information about The Formulary Monograph Service, call The Formulary at 800-322-4349. The June 2014 monograph topics are apremilast, metreleptin, five pollen allergen extract, evolocumab, and miltefosine. The DUE/MUE is on apremilast.

Entities:  

Year:  2014        PMID: 24958974      PMCID: PMC4062736          DOI: 10.1310/hpj4906-554

Source DB:  PubMed          Journal:  Hosp Pharm        ISSN: 0018-5787


  13 in total

1.  A randomized, double-blind dose-ranging study of the novel LAMA GSK573719 in patients with COPD.

Authors:  James F Donohue; Antonio Anzueto; Jean Brooks; Rashmi Mehta; Christopher Kalberg; Glenn Crater
Journal:  Respir Med       Date:  2012-04-10       Impact factor: 3.415

2.  Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases.

Authors:  Michael Salmon; Mark A Luttmann; James J Foley; Peter T Buckley; Dulcie B Schmidt; Miriam Burman; Edward F Webb; Christopher J DeHaas; Charles J Kotzer; Victoria J Barrett; Robert J Slack; Henry M Sarau; Michael R Palovich; Dramane I Lainé; Douglas W P Hay; William L Rumsey
Journal:  J Pharmacol Exp Ther       Date:  2013-02-22       Impact factor: 4.030

3.  24-h duration of the novel LABA vilanterol trifenatate in asthma patients treated with inhaled corticosteroids.

Authors:  Jan Lötvall; Eric D Bateman; Eugene R Bleecker; William W Busse; Ashley Woodcock; Richard Follows; Jessica Lim; Sally Stone; Loretta Jacques; Brett Haumann
Journal:  Eur Respir J       Date:  2012-02-23       Impact factor: 16.671

4.  Bronchodilation of umeclidinium, a new long-acting muscarinic antagonist, in COPD patients.

Authors:  Marc Decramer; François Maltais; Gregory Feldman; Jean Brooks; Stephanie Harris; Rashmi Mehta; Glenn Crater
Journal:  Respir Physiol Neurobiol       Date:  2012-09-28       Impact factor: 1.931

5.  Efficacy and safety of once-daily umeclidinium/vilanterol 62.5/25 mcg in COPD.

Authors:  J F Donohue; M R Maleki-Yazdi; S Kilbride; R Mehta; C Kalberg; A Church
Journal:  Respir Med       Date:  2013-07-02       Impact factor: 3.415

6.  Vilanterol trifenatate, a novel inhaled long-acting beta2 adrenoceptor agonist, is well tolerated in healthy subjects and demonstrates prolonged bronchodilation in subjects with asthma and COPD.

Authors:  Rodger Kempsford; Virginia Norris; Sarah Siederer
Journal:  Pulm Pharmacol Ther       Date:  2012-12-08       Impact factor: 3.410

7.  Metabolism and disposition of vilanterol, a long-acting β(2)-adrenoceptor agonist for inhalation use in humans.

Authors:  Andrew W Harrell; Sarah K Siederer; Jo Bal; Nainesh H Patel; Graeme C Young; Clive C Felgate; Sebastian J Pearce; Andy D Roberts; Claire Beaumont; Amanda J Emmons; Adrian I Pereira; Rodger D Kempsford
Journal:  Drug Metab Dispos       Date:  2012-10-04       Impact factor: 3.922

8.  28-Day safety and tolerability of umeclidinium in combination with vilanterol in COPD: a randomized placebo-controlled trial.

Authors:  Gregory Feldman; Robert R Walker; Jean Brooks; Rashmi Mehta; Glenn Crater
Journal:  Pulm Pharmacol Ther       Date:  2012-08-31       Impact factor: 3.410

9.  Once-daily umeclidinium/vilanterol 125/25 mcg in COPD: a randomized, controlled study.

Authors:  Bartolome Celli; Glenn Crater; Sally Kilbride; Rashmi Mehta; Maggie Tabberer; Chris J Kalberg; Alison Church
Journal:  Chest       Date:  2014-05       Impact factor: 9.410

10.  Safety, tolerability, pharmacodynamics and pharmacokinetics of umeclidinium and vilanterol alone and in combination: a randomized crossover trial.

Authors:  Dennis L Kelleher; Rashmi S Mehta; Bernadette M Jean-Francois; Andrew F Preece; James Blowers; Glenn D Crater; Paul Thomas
Journal:  PLoS One       Date:  2012-12-17       Impact factor: 3.240

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