| Literature DB >> 2495769 |
A Del Corso1, D Barsacchi, M Camici, D Garland, U Mura.
Abstract
Two structurally different forms of bovine lens aldose reductase have been identified. Freshly prepared lens extracts contain an unactivated "b form" (ARb) which is sensitive to inhibition by Sorbinil. Upon incubation of the extracts with oxygen radical generating systems, ARb is converted to a more active "a form" (ARa), which is not inhibited by Sorbinil. ARa and ARb were purified to electrophoretic homogeneity.Entities:
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Year: 1989 PMID： 2495769 DOI： 10.1016/0003-9861(89)90543-2
Source DB: PubMed Journal: Arch Biochem Biophys ISSN： 0003-9861 Impact factor: 4.013