| Literature DB >> 2495743 |
B J Gesink-van der Veer1, A G Burm, P J Hennis, J G Bovill.
Abstract
The dose requirement of alfentanil as a supplement to nitrous oxide anaesthesia was studied in 13 patients with Crohn's disease and seven control patients all of whom underwent laparotomy. Alfentanil was administered as a variable rate infusion with supplemental bolus injections titrated to the patient's needs. The alfentanil requirement was independent of the duration of surgery and was significantly higher in patients with Crohn's disease than in control patients. The results indicate that Crohn's disease alters the dose requirement of alfentanil.Entities:
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Year: 1989 PMID： 2495743 DOI： 10.1111/j.1365-2044.1989.tb11224.x
Source DB: PubMed Journal: Anaesthesia ISSN： 0003-2409 Impact factor: 6.955