| Literature DB >> 24957412 |
Christian Marinaccio1, Beatrice Nico1, Eugenio Maiorano2, Giorgina Specchia3, Domenico Ribatti4.
Abstract
Angiogenesis is a hallmark of tumor growth and progression in solid and hematological malignancies. Different cellular components of the tumor microenvironment such as macrophages, mast cells, circulating endothelial cells and angiogenic factors, including vascular endothelial growth factor and its receptors are involved in the maintenance of Hodgkin Lymphoma. In this review article, we highlight relevant literature focusing on the relationships between angiogenesis and Hodgkin Lymphoma as well as discussing anti-angiogenic treatments in this malignancy.Entities:
Keywords: Angiogenesis; Anti-angiogenesis; Hodgkin Lymphoma; Tumor microenvironment
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Year: 2014 PMID: 24957412 DOI: 10.1016/j.leukres.2014.05.023
Source DB: PubMed Journal: Leuk Res ISSN: 0145-2126 Impact factor: 3.156