Literature DB >> 24956352

Palladium-catalyzed formylation of aryl halides with tert-butyl isocyanide.

Xiao Jiang1, Jin-Mei Wang, Ying Zhang, Zhong Chen, Yong-Ming Zhu, Shun-Jun Ji.   

Abstract

A novel palladium-catalyzed formylation of aryl halides with isocyanide in the presence of Et3SiH has been demonstrated, which provides a strategy toward important aldehydes with moderate to excellent yield. The advantage of this reaction includes milder conditions, convenient operation, lower toxicity, and wide functional group tolerance.

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Year:  2014        PMID: 24956352     DOI: 10.1021/ol5014262

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  5 in total

1.  Mild, Redox-Neutral Formylation of Aryl Chlorides through the Photocatalytic Generation of Chlorine Radicals.

Authors:  Matthew K Nielsen; Benjamin J Shields; Junyi Liu; Michael J Williams; Michael J Zacuto; Abigail G Doyle
Journal:  Angew Chem Int Ed Engl       Date:  2017-05-23       Impact factor: 15.336

2.  Access to 1-amino-3,4-dihydroisoquinolines via palladium-catalyzed C-H bond aminoimidoylation reaction from functionalized isocyanides.

Authors:  Zhuang Xiong; Panyuan Cai; Yingshuang Mei; Jian Wang
Journal:  RSC Adv       Date:  2019-12-18       Impact factor: 4.036

3.  A 16-step synthesis of the isoryanodane diterpene (+)-perseanol.

Authors:  Arthur Han; Yujia Tao; Sarah E Reisman
Journal:  Nature       Date:  2019-09-25       Impact factor: 49.962

4.  Nickel-catalyzed allylic carbonylative coupling of alkyl zinc reagents with tert-butyl isocyanide.

Authors:  Yangyang Weng; Chenhuan Zhang; Zaiquan Tang; Mohini Shrestha; Wenyi Huang; Jingping Qu; Yifeng Chen
Journal:  Nat Commun       Date:  2020-01-20       Impact factor: 14.919

Review 5.  Recent Advances in Palladium-Catalyzed Isocyanide Insertions.

Authors:  Jurriën W Collet; Thomas R Roose; Bram Weijers; Bert U W Maes; Eelco Ruijter; Romano V A Orru
Journal:  Molecules       Date:  2020-10-23       Impact factor: 4.411

  5 in total

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