Literature DB >> 24954566

Hyperbolic Dirac Nets for medical decision support. Theory, methods, and comparison with Bayes Nets.

Barry Robson1.   

Abstract

We recently introduced the concept of a Hyperbolic Dirac Net (HDN) for medical inference on the grounds that, while the traditional Bayes Net (BN) is popular in medicine, it is not suited to that domain: there are many interdependencies such that any "node" can be ultimately conditional upon itself. A traditional BN is a directed acyclic graph by definition, while the HDN is a bidirectional general graph closer to a diffuse "field" of influence. Cycles require bidirectionality; the HDN uses a particular type of imaginary number from Dirac׳s quantum mechanics to encode it. Comparison with the BN is made alongside a set of recipes for converting a given BN to an HDN, also adding cycles that do not usually require reiterative methods. This conversion is called the P-method. Conversion to cycles can sometimes be difficult, but more troubling was that the original BN had probabilities needing adjustment to satisfy realism alongside the important property called "coherence". The more general and simpler K-method, not dependent on the BN, is usually (but not necessarily) derived by data mining, and is therefore also introduced. As discussed, BN developments may converge to an HDN-like concept, so it is reasonable to consider the HDN as a BN extension.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Keywords:  Bayes Net; Complex; Decision support system; Dirac; Expert system; Hyperbolic; Hyperbolic Dirac Net; Medical inference

Mesh:

Year:  2014        PMID: 24954566     DOI: 10.1016/j.compbiomed.2014.03.014

Source DB:  PubMed          Journal:  Comput Biol Med        ISSN: 0010-4825            Impact factor:   4.589


  4 in total

1.  Data-mining to build a knowledge representation store for clinical decision support. Studies on curation and validation based on machine performance in multiple choice medical licensing examinations.

Authors:  Barry Robson; Srinidhi Boray
Journal:  Comput Biol Med       Date:  2016-02-26       Impact factor: 4.589

Review 2.  Towards faster response against emerging epidemics and prediction of variants of concern.

Authors:  B Robson
Journal:  Inform Med Unlocked       Date:  2022-05-20

3.  Bioinformatics studies on a function of the SARS-CoV-2 spike glycoprotein as the binding of host sialic acid glycans.

Authors:  B Robson
Journal:  Comput Biol Med       Date:  2020-06-08       Impact factor: 4.589

4.  Computers and viral diseases. Preliminary bioinformatics studies on the design of a synthetic vaccine and a preventative peptidomimetic antagonist against the SARS-CoV-2 (2019-nCoV, COVID-19) coronavirus.

Authors:  B Robson
Journal:  Comput Biol Med       Date:  2020-02-26       Impact factor: 4.589

  4 in total

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