Lubna Abbasi1, Fakhir Raza Haidri2. 1. Department of Medicine, The Indus Hospital, Karachi. 2. Department of Medicine, Sindh Institute of Urology and Transplantation, Karachi.
Abstract
OBJECTIVE: To evaluate frequency of fibromyalgia in rheumatoid arthritis and its effect on disease activity score. STUDY DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: The Indus Hospital, Karachi, from December 2010 to May 2011. METHODOLOGY: All adult patients of either gender diagnosed as rheumatoid arthritis on the basis of clinical, laboratory and X-ray criteria were included in the study. The sample data was separated into two groups depending on presence or absence of fibromyalgia and 28 joint disease activity score (DAS-28) value was evaluated. RESULTS: There were 31 (25.83%) patients with rheumatoid arthritis and fibromyalgia (RAFM) out of the total 120. The median (IQR) age of patients was 40 (32 - 51) years. All were females. The overall female frequency was 79 (88.8%). The median (IQR) DAS-28 score in RA group was 4.9 (3.66 - 5.71), while the median (IQR) DAS-28 score in RAFM was 7.04 (6.62 - 7.64) [p < 0.0001]. The number of patient getting combination therapy of DMARD in RAFM group was 61.3% while in RA group was 42.7%. CONCLUSION: DAS-28 was found to be significantly higher in RAFM patients probably because of higher perception of pain.
OBJECTIVE: To evaluate frequency of fibromyalgia in rheumatoid arthritis and its effect on disease activity score. STUDY DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: The Indus Hospital, Karachi, from December 2010 to May 2011. METHODOLOGY: All adult patients of either gender diagnosed as rheumatoid arthritis on the basis of clinical, laboratory and X-ray criteria were included in the study. The sample data was separated into two groups depending on presence or absence of fibromyalgia and 28 joint disease activity score (DAS-28) value was evaluated. RESULTS: There were 31 (25.83%) patients with rheumatoid arthritis and fibromyalgia (RAFM) out of the total 120. The median (IQR) age of patients was 40 (32 - 51) years. All were females. The overall female frequency was 79 (88.8%). The median (IQR) DAS-28 score in RA group was 4.9 (3.66 - 5.71), while the median (IQR) DAS-28 score in RAFM was 7.04 (6.62 - 7.64) [p < 0.0001]. The number of patient getting combination therapy of DMARD in RAFM group was 61.3% while in RA group was 42.7%. CONCLUSION: DAS-28 was found to be significantly higher in RAFM patients probably because of higher perception of pain.
Authors: Hyein Kim; Jing Cui; Michelle Frits; Christine Iannaccone; Jonathan Coblyn; Nancy A Shadick; Michael E Weinblatt; Yvonne C Lee Journal: Arthritis Care Res (Hoboken) Date: 2017-11-14 Impact factor: 4.794