| Literature DB >> 24952957 |
Signe M Jensen1, Christian Ritz.
Abstract
Model averaging is a useful approach for capturing uncertainty due to model selection. Currently, this uncertainty is often quantified by means of approximations that do not easily extend to simultaneous inference. Moreover, in practice there is a need for both model averaging and simultaneous inference for derived parameters calculated in an after-fitting step. We propose a method for obtaining asymptotically correct standard errors for one or several model-averaged estimates of derived parameters and for obtaining simultaneous confidence intervals that asymptotically control the family-wise Type I error rate. The performance of the method in terms of coverage is evaluated using a simulation study and the applicability of the method is demonstrated by means of three concrete examples.Keywords: Asymptotic representation; Wald-type intervals; benchmark dose; coverage; dose response
Year: 2014 PMID: 24952957 DOI: 10.1111/risa.12242
Source DB: PubMed Journal: Risk Anal ISSN: 0272-4332 Impact factor: 4.000