Literature DB >> 24951612

A thalassaemia intermedia case with concomitant left atrial thrombus.

Cem Sahin1, Ozcan Basaran2, Yasar Topal3, Fatih Akin4.   

Abstract

Although marked improvements have been observed in the life expectancy of patients with thalassaemia by regular blood transfusion and strict iron chelation therapies in recent years, these patients still have to deal with several complications, mainly cardiovascular. One of the life-threatening complications is the chronic hypercoagulable state and thromboembolic events which develop due to haemostatic alterations in patients with thalassaemia, although they are more frequently seen in those with thalassaemia intermedia. Many thromboembolic complications, mainly deep venous thrombosis and cerebral thrombosis, have been reported in thalassaemia. However, intracardiac thrombosis is rarely seen. In this manuscript, we presented a case that underwent splenectomy 6 years ago but not regularly attended the control visits and presented to our clinic with gradually increasing exercise dyspnoea for 2 months. 2014 BMJ Publishing Group Ltd.

Entities:  

Mesh:

Year:  2014        PMID: 24951612      PMCID: PMC4069792          DOI: 10.1136/bcr-2013-203106

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

1.  Risk factors for pulmonary hypertension in patients with β thalassemia intermedia.

Authors:  Mehran Karimi; Khaled M Musallam; Maria Domenica Cappellini; Shahina Daar; Amal El-Beshlawy; Khawla Belhoul; Mohamed-Salaheldin Saned; Sally Temraz; Suzanne Koussa; Ali T Taher
Journal:  Eur J Intern Med       Date:  2011-06-29       Impact factor: 4.487

2.  Pulmonary hypertension in thalassemia: association with platelet activation and hypercoagulable state.

Authors:  Sylvia T Singer; Frans A Kuypers; Lori Styles; Elliott P Vichinsky; Drucella Foote; Howard Rosenfeld
Journal:  Am J Hematol       Date:  2006-09       Impact factor: 10.047

3.  Thromboembolic events in beta thalassemia major: an Italian multicenter study.

Authors:  C Borgna Pignatti; V Carnelli; V Caruso; F Dore; D De Mattia; A Di Palma; F Di Gregorio; M A Romeo; R Longhi; A Mangiagli; C Melevendi; G Pizzarelli; S Musumeci
Journal:  Acta Haematol       Date:  1998       Impact factor: 2.195

4.  Thromboembolism in beta-thalassemia major.

Authors:  N Akar; S Kemahli; Z Uysal; S Cin
Journal:  Acta Haematol       Date:  1998-12       Impact factor: 2.195

5.  Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran.

Authors:  Ali Taher; Hussain Isma'eel; Ghassan Mehio; Daniela Bignamini; Antonis Kattamis; Eliezer A Rachmilewitz; Maria Domenica Cappellini
Journal:  Thromb Haemost       Date:  2006-10       Impact factor: 5.249

6.  Venous thromboembolism and hypercoagulability in splenectomized patients with thalassaemia intermedia.

Authors:  M D Cappellini; L Robbiolo; B M Bottasso; R Coppola; G Fiorelli; A P Mannucci
Journal:  Br J Haematol       Date:  2000-11       Impact factor: 6.998

Review 7.  Redefining thalassemia as a hypercoagulable state.

Authors:  M Domenica Cappellini; Irene Motta; Khaled M Musallam; Ali T Taher
Journal:  Ann N Y Acad Sci       Date:  2010-08       Impact factor: 5.691

Review 8.  Pulmonary thromboembolism in beta-thalassemia intermedia: are we aware of this complication?

Authors:  Ali Taher; Yasser Abou-Mourad; Antoine Abchee; Pierre Zalouaa; Ali Shamseddine
Journal:  Hemoglobin       Date:  2002-05       Impact factor: 0.849

9.  Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT).

Authors:  Nazzareno Galiè; Marius M Hoeper; Marc Humbert; Adam Torbicki; Jean-Luc Vachiery; Joan Albert Barbera; Maurice Beghetti; Paul Corris; Sean Gaine; J Simon Gibbs; Miguel Angel Gomez-Sanchez; Guillaume Jondeau; Walter Klepetko; Christian Opitz; Andrew Peacock; Lewis Rubin; Michael Zellweger; Gerald Simonneau
Journal:  Eur Heart J       Date:  2009-08-27       Impact factor: 29.983

Review 10.  Thalassemia and hypercoagulability.

Authors:  Ali T Taher; Zaher K Otrock; Imad Uthman; Maria D Cappellini
Journal:  Blood Rev       Date:  2008-06-03       Impact factor: 8.250

  10 in total

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