Literature DB >> 24950390

HKOCl-2 series of green BODIPY-based fluorescent probes for hypochlorous acid detection and imaging in live cells.

Jun Jacob Hu1, Nai-Kei Wong, Qiangshuai Gu, Xiaoyu Bai, Sen Ye, Dan Yang.   

Abstract

A HKOCl-2 series of new fluorescent probes for hypochlorous acid (HOCl) detection in live cells is reported. The probes exhibit excellent selectivity, sensitivity, and chemostability toward HOCl. In particular, HKOCl-2b rapidly and selectively detects endogenous HOCl in both human and mouse macrophages. These probes could therefore serve as promising discovery tools to help elucidate biological functions of HOCl.

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Year:  2014        PMID： 24950390     DOI： 10.1021/ol501496n

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  10 in total

1.  Synthesis and spectroscopic properties of β,β'-dibenzo-3,5,8-triaryl-BODIPYs.

Authors:  Qianli Meng; Frank R Fronczek; M Graça H Vicente
Journal:  New J Chem       Date:  2016-02-08       Impact factor: 3.591

Review 2.  Challenges and Opportunities for Small-Molecule Fluorescent Probes in Redox Biology Applications.

Authors:  Xiqian Jiang; Lingfei Wang; Shaina L Carroll; Jianwei Chen; Meng C Wang; Jin Wang
Journal:  Antioxid Redox Signal       Date:  2018-02-16       Impact factor: 8.401

3.  Mitochondrial-Targeted Ratiometric Fluorescent Probe to Monitor ClO- Induced by Ferroptosis in Living Cells.

Authors:  Beidou Feng; Kui Wang; Zhe Wang; Huiyu Niu; Ge Wang; Yuehua Chen; Hua Zhang
Journal:  Front Chem       Date:  2022-06-09       Impact factor: 5.545

Review 4.  Recent progress in chromogenic and fluorogenic chemosensors for hypochlorous acid.

Authors:  Yongkang Yue; Fangjun Huo; Caixia Yin; Jorge O Escobedo; Robert M Strongin
Journal:  Analyst       Date:  2016-03-21       Impact factor: 4.616

5.  HOCl can appear in the mitochondria of macrophages during bacterial infection as revealed by a sensitive mitochondrial-targeting fluorescent probe.

Authors:  Jin Zhou; Lihong Li; Wen Shi; Xinghui Gao; Xiaohua Li; Huimin Ma
Journal:  Chem Sci       Date:  2015-06-01       Impact factor: 9.825

6.  Overriding Phthalate Decomposition When Exploring Mycophenolic Acid Intermediates as Selenium-Based ROS Biological Probes.

Authors:  Mahesh B Halle; Tesla Yudhistira; Kyung Jin Lee; Jae Hyuck Choi; Youngsam Kim; Hee-Sung Park; David G Churchill
Journal:  ACS Omega       Date:  2018-10-18

Review 7.  The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture.

Authors:  Nathaniel Teng; Ghassan J Maghzal; Jihan Talib; Imran Rashid; Antony K Lau; Roland Stocker
Journal:  Redox Rep       Date:  2016-11-25       Impact factor: 4.412

8.  HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay.

Authors:  Jun Jacob Hu; Nai-Kei Wong; Ming-Yang Lu; Xingmiao Chen; Sen Ye; Angela Qian Zhao; Peng Gao; Richard Yi-Tsun Kao; Jiangang Shen; Dan Yang
Journal:  Chem Sci       Date:  2016-01-06       Impact factor: 9.825

9.  Deformylation reaction-based probe for in vivo imaging of HOCl.

Authors:  Peng Wei; Wei Yuan; Fengfeng Xue; Wei Zhou; Ruohan Li; Datong Zhang; Tao Yi
Journal:  Chem Sci       Date:  2017-11-03       Impact factor: 9.825

10.  Malononitrile as the 'double-edged sword' of passivation-activation regulating two ICT to highly sensitive and accurate ratiometric fluorescent detection for hypochlorous acid in biological system.

Authors:  Yan Shi; Fangjun Huo; Caixia Yin
Journal:  Sens Actuators B Chem       Date:  2020-08-25       Impact factor: 7.460
  10 in total

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