Literature DB >> 24949964

From cancer genomics to precision oncology--tissue's still an issue.

Robert L Cohen1, Jeff Settleman2.   

Abstract

Rapidly evolving genome technology has enabled extensive molecular analysis of limited tumor biopsy material, thereby facilitating the broader implementation of personalized cancer medicine. However, genomics-based patient stratification across diverse tumor types is unlikely to supplant tissue-of-origin considerations in addressing clinical needs, including the development and application of novel "rationally targeted" cancer therapies.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 24949964     DOI: 10.1016/j.cell.2014.05.027

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  17 in total

Review 1.  Molecular subtypes in cancers of the gastrointestinal tract.

Authors:  Maarten F Bijlsma; Anguraj Sadanandam; Patrick Tan; Louis Vermeulen
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2017-04-12       Impact factor: 46.802

2.  Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities.

Authors:  Jean-Philippe Coppé; Miki Mori; Bo Pan; Christina Yau; Denise M Wolf; Ana Ruiz-Saenz; Diede Brunen; Anirudh Prahallad; Paulien Cornelissen-Steijger; Kristel Kemper; Christian Posch; Changjun Wang; Courtney A Dreyer; Oscar Krijgsman; Pei Rong Evelyn Lee; Zhongzhong Chen; Daniel S Peeper; Mark M Moasser; René Bernards; Laura J van 't Veer
Journal:  Nat Cell Biol       Date:  2019-06-03       Impact factor: 28.824

3.  Characterization of cytokinome landscape for clinical responses in human cancers.

Authors:  Henry Sung-Ching Wong; Che-Mai Chang; Xiao Liu; Wan-Chen Huang; Wei-Chiao Chang
Journal:  Oncoimmunology       Date:  2016-11-04       Impact factor: 8.110

4.  Clinical Applications and Utility of a Precision Medicine Approach for Patients With Unexplained Cytopenias.

Authors:  Abhishek A Mangaonkar; Alejandro Ferrer; Filippo Pinto E Vairo; Margot A Cousin; Ryan J Kuisle; Naseema Gangat; William J Hogan; Mark R Litzow; Tammy M McAllister; Eric W Klee; Konstantinos N Lazaridis; A Keith Stewart; Mrinal M Patnaik
Journal:  Mayo Clin Proc       Date:  2019-06-27       Impact factor: 7.616

Review 5.  Translational research in oncology--10 years of progress and future prospects.

Authors:  James H Doroshow; Shivaani Kummar
Journal:  Nat Rev Clin Oncol       Date:  2014-10-07       Impact factor: 66.675

6.  Tissue specificity of in vitro drug sensitivity.

Authors:  Fupan Yao; Seyed Ali Madani Tonekaboni; Zhaleh Safikhani; Petr Smirnov; Nehme El-Hachem; Mark Freeman; Venkata Satya Kumar Manem; Benjamin Haibe-Kains
Journal:  J Am Med Inform Assoc       Date:  2018-02-01       Impact factor: 4.497

Review 7.  Tissue-specific tumorigenesis: context matters.

Authors:  Günter Schneider; Marc Schmidt-Supprian; Roland Rad; Dieter Saur
Journal:  Nat Rev Cancer       Date:  2017-03-03       Impact factor: 60.716

8.  Just like the rest of evolution in Mother Nature, the evolution of cancers may be driven by natural selection, and not by haphazard mutations.

Authors:  Ju Zhang; Xiaomin Lou; Lucas Zellmer; Siqi Liu; Ningzhi Xu; D Joshua Liao
Journal:  Oncoscience       Date:  2014-09-22

Review 9.  Precision Medicine Gains Momentum: Novel 3D Models and Stem Cell-Based Approaches in Head and Neck Cancer.

Authors:  Annette Affolter; Anne Lammert; Johann Kern; Claudia Scherl; Nicole Rotter
Journal:  Front Cell Dev Biol       Date:  2021-07-08

10.  HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B.

Authors:  Daniel C Kirouac; Jinyan Du; Johanna Lahdenranta; Matthew D Onsum; Ulrik B Nielsen; Birgit Schoeberl; Charlotte F McDonagh
Journal:  PLoS Comput Biol       Date:  2016-04-01       Impact factor: 4.475

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