Uwe Wollina1, Jaqueline Schönlebe2, Mirjana Ziemer3, Franziska Friedling4, André Koch1, Gunter Haroske2, Martin Kaatz4, Jan-C Simon3. 1. Department of Dermatology and Allergology, Hospital Dresden-Friedrichstadt, Academic Teaching Hospital of the Technical University of Dresden, Dresden, Germany. 2. Institute of Pathology "Georg Schmorl," Hospital Dresden-Friedrichstadt, Academic Teaching Hospital of the Technical University of Dresden, Dresden, Germany. 3. Department of Dermatology, Venereology, and Allergology, University of Leipzig, Leipzig, Germany. 4. Department of Dermatology and Allergology, SHR-Waldklinikum, Gera, Germany.
Abstract
BACKGROUND: Atypical fibroxanthoma is a rare mesenchymal tumor of the head and neck region. METHODS: We analyzed the files of 3 large dermatology hospitals from the years 2001 to 2013 in southeast Germany. RESULTS: We identified 53 patients (56 tumors) with a male predominance. The mean age was 78.0 years ± 8.3 years. Mohs surgery was performed in all cases resulting in complete remission in 45 patients. Five patients had a relapse within 2 years, and 4 developed metastases. None of the tumors with a safety margin of ≥2 cm relapsed. The majority of cases were found in the Dresden region. CONCLUSION: Atypical fibroxanthoma demonstrates an uneven geographic distribution in southeast Germany that demands further investigations. Mohs surgery with ≥2 cm safety margins is the treatment of choice. A regular follow-up is recommended.
BACKGROUND:Atypical fibroxanthoma is a rare mesenchymal tumor of the head and neck region. METHODS: We analyzed the files of 3 large dermatology hospitals from the years 2001 to 2013 in southeast Germany. RESULTS: We identified 53 patients (56 tumors) with a male predominance. The mean age was 78.0 years ± 8.3 years. Mohs surgery was performed in all cases resulting in complete remission in 45 patients. Five patients had a relapse within 2 years, and 4 developed metastases. None of the tumors with a safety margin of ≥2 cm relapsed. The majority of cases were found in the Dresden region. CONCLUSION:Atypical fibroxanthoma demonstrates an uneven geographic distribution in southeast Germany that demands further investigations. Mohs surgery with ≥2 cm safety margins is the treatment of choice. A regular follow-up is recommended.
Authors: Mathias Ørholt; Frederik L Aaberg; Kiya Abebe; S Walsh; Randall K Roenigk; Alessandro Venzo; Grethe Schmidt; Helle Klyver; David H Jensen; Mikkel Herly; Peter V Vester-Glowinski Journal: J Surg Oncol Date: 2022-04-19 Impact factor: 2.885