Literature DB >> 24946109

Surgical management of hepatic hemangiomas: a multi-institutional experience.

John T Miura1, Albert Amini, Ryan Schmocker, Shawnn Nichols, Daniel Sukato, Emily R Winslow, Gaya Spolverato, Aslam Ejaz, Malcolm H Squires, David A Kooby, Shishir K Maithel, Aijun Li, Meng-Chao Wu, Juan M Sarmiento, Mark Bloomston, Kathleen K Christians, Fabian M Johnston, Susan Tsai, Kiran K Turaga, Allan Tsung, Timothy M Pawlik, T Clark Gamblin.   

Abstract

BACKGROUND: The management of hepatic hemangiomas remains ill defined. This study sought to investigate the indications, surgical management and outcomes of patients who underwent a resection for hepatic hemangiomas.
METHODS: A retrospective review from six major liver centres in the United States identifying patients who underwent surgery for hepatic hemangiomas was performed. Clinico-pathological, treatment and peri-operative data were evaluated.
RESULTS: Of the 241patients who underwent a resection, the median age was 46 years [interquartile range (IQR): 39-53] and 85.5% were female. The median hemangioma size was 8.5 cm (IQR: 6-12.1). Surgery was performed for abdominal symptoms (85%), increasing hemangioma size (11.3%) and patient anxiety (3.7%). Life-threatening complications necessitating a hemangioma resection occurred in three patients (1.2%). Clavien Grade 3 or higher complications occurred in 14 patients (5.7%). The 30- and 90-day mortality was 0.8% (n = 2). Of patients with abdominal symptoms, 63.2% reported improvement of symptoms post-operatively.
CONCLUSION: A hemangioma resection can be safely performed at high-volume institutions. The primary indication for surgery remains for intractable symptoms. The development of severe complications associated with non-operative management remains a rare event, ultimately challenging the necessity of additional surgical indications for a hemangioma resection.
© 2014 International Hepato-Pancreato-Biliary Association.

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Year:  2014        PMID: 24946109      PMCID: PMC4238859          DOI: 10.1111/hpb.12291

Source DB:  PubMed          Journal:  HPB (Oxford)        ISSN: 1365-182X            Impact factor:   3.647


  13 in total

Review 1.  The diagnosis and management of benign hepatic tumors.

Authors:  Bo Yoon Choi; Mindie H Nguyen
Journal:  J Clin Gastroenterol       Date:  2005 May-Jun       Impact factor: 3.062

2.  Improvements in quality of life after surgery for benign hepatic tumors: Results from a dual center analysis.

Authors:  Peter J Kneuertz; J Wallis Marsh; Mechteld C de Jong; Keaton Covert; Omar Hyder; Kenzo Hirose; Richard D Schulick; Michael A Choti; David A Geller; Timothy M Pawlik
Journal:  Surgery       Date:  2012-08       Impact factor: 3.982

3.  Size of lesion is not a criterion for resection during management of giant liver haemangioma.

Authors:  T Terkivatan; W W Vrijland; P T Den Hoed; R A De Man; S M Hussain; H W Tilanus; J N M IJzermans
Journal:  Br J Surg       Date:  2002-10       Impact factor: 6.939

4.  Management of giant hemangioma of the liver: resection versus observation.

Authors:  Thomas Schnelldorfer; Adam L Ware; Rory Smoot; Cathy D Schleck; William S Harmsen; David M Nagorney
Journal:  J Am Coll Surg       Date:  2010-10-25       Impact factor: 6.113

5.  Benign lesions of the liver.

Authors:  P J Mergo; P R Ros
Journal:  Radiol Clin North Am       Date:  1998-03       Impact factor: 2.303

6.  Hepatic metastases and cavernous hemangiomas: distinction with standard- and triple-dose gadoteridol-enhanced MR imaging.

Authors:  D G Mitchell; S Saini; J Weinreb; E E De Lange; V M Runge; J E Kuhlman; Y Parisky; C D Johnson; J J Brown; M Schnall
Journal:  Radiology       Date:  1994-10       Impact factor: 11.105

Review 7.  A review of liver masses in pregnancy and a proposed algorithm for their diagnosis and management.

Authors:  Frederick C Cobey; Ronald R Salem
Journal:  Am J Surg       Date:  2004-02       Impact factor: 2.565

8.  Management of liver hemangiomas according to size and symptoms.

Authors:  Deha Erdogan; Olivier R C Busch; Otto M van Delden; Roelof J Bennink; Fiebo J W ten Kate; Dirk J Gouma; Thomas M van Gulik
Journal:  J Gastroenterol Hepatol       Date:  2007-11       Impact factor: 4.029

9.  Hepatic haemangiomas: possible association with female sex hormones.

Authors:  V Glinkova; O Shevah; M Boaz; A Levine; H Shirin
Journal:  Gut       Date:  2004-09       Impact factor: 23.059

10.  Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey.

Authors:  Daniel Dindo; Nicolas Demartines; Pierre-Alain Clavien
Journal:  Ann Surg       Date:  2004-08       Impact factor: 12.969

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  23 in total

1.  Superselective Transarterial Chemoembolization as an Alternative to Surgery in Symptomatic/Enlarging Liver Hemangiomas.

Authors:  İlgin Özden; Arzu Poyanlı; Yılmaz Önal; Ali Aslan Demir; Gültekin Hoş; Bülent Acunaş
Journal:  World J Surg       Date:  2017-11       Impact factor: 3.352

2.  Surgical Management of Giant Hepatic Hemangioma: Single Center's Experience with 144 Patients.

Authors:  Mohamed Abdel Wahab; Ayman El Nakeeb; Mahmoud Abdelwahab Ali; Youssef Mahdy; Ahmed Shehta; Mohamed Abdulrazek; Mohamed El Desoky; Rihame Abdel Wahab
Journal:  J Gastrointest Surg       Date:  2018-02-27       Impact factor: 3.452

3.  Revisiting the Surgical Management of Giant Hepatic Hemangiomas: Enucleation Versus Anatomical Resection?

Authors:  Muthukumarassamy Rajakannu; Gerard Pascal; Denis Castaing; Eric Vibert; Christian Ducerf; Jean-Yves Mabrut; Jacques Baulieux; René Adam
Journal:  J Clin Exp Hepatol       Date:  2020-10-02

4.  Giant Hepatic Hemangioma Causing Prolonged Fever and Indicated for Resection.

Authors:  Chihiro Yoshimizu; Shunichi Ariizumi; Tomomi Kogiso; Takaomi Sagawa; Makiko Taniai; Goro Honda; Hiroto Egawa; Katsutoshi Tokushige
Journal:  Intern Med       Date:  2021-11-20       Impact factor: 1.282

5.  A giant cavernous hemangioma of the liver extending into the pelvis.

Authors:  Jiayi Kong; Daniel A Anaya
Journal:  Int J Surg Case Rep       Date:  2015-06-19

6.  Computed Tomography-Guided Radiofrequency Ablation Following Transcatheter Arterial Embolization in Treatment of Large Hepatic Hemangiomas.

Authors:  Jiansong Ji; Jun Gao; Lizhen Zhao; Jianfei Tu; Jingjing Song; Wenbing Sun
Journal:  Medicine (Baltimore)       Date:  2016-04       Impact factor: 1.889

7.  Laparoscopic Radiofrequency Ablation for Large Subcapsular Hepatic Hemangiomas: Technical and Clinical Outcomes.

Authors:  Jun Gao; Jian-Song Ji; Xue-Mei Ding; Shan Ke; Zong-Hai Xin; Chun-Min Ning; Shi-Gang Guo; Xiao-Long Li; Yong-Hong Dong; Wen-Bing Sun
Journal:  PLoS One       Date:  2016-02-22       Impact factor: 3.240

8.  Case report: successful open resection of a symptomatic giant liver haemangioma during the second trimester of pregnancy.

Authors:  Angus Hann; Edoardo Osenda; Jon A Reade; Demetrius Economides; Dinesh Sharma
Journal:  J Surg Case Rep       Date:  2016-11-24

Review 9.  Benign Liver Tumors.

Authors:  Karl J Oldhafer; Victoria Habbel; Katja Horling; Georgios Makridis; Kim Caroline Wagner
Journal:  Visc Med       Date:  2020-08-04

10.  Treatment of atypically-localized cavernous hemangioma in abdomen with atypical pain.

Authors:  Mehmet Ilhan; Gizem Oner; Ali Fuat Kaan Gök; Mesut Bulakçı; Gülçin Yeğen
Journal:  Int J Surg Case Rep       Date:  2016-06-07
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