Shelley S Magill1, Barry Rhodes, Michael Klompas. 1. aDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia bDepartment of Population Medicine, Harvard Medical School, Harvard Pilgrim Healthcare Institute cDepartment of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Abstract
PURPOSE OF REVIEW: The Centers for Disease Control and Prevention (CDC) recently transitioned from ventilator-associated pneumonia (VAP) surveillance to ventilator-associated event (VAE) surveillance in adult inpatient settings. Since the transition, several modifications have been made to improve surveillance methods, and there is a growing body of data regarding the epidemiology, risk factors, and preventability of VAEs. RECENT FINDINGS: The VAE surveillance definition algorithm is based on objective criteria and includes three tiers: ventilator-associated conditions, infection-related ventilator-associated complications, and possible and probable VAP. VAE surveillance expands the purview of surveillance beyond pneumonia alone to include additional complications of mechanical ventilation. Most VAEs are caused by pneumonia, pulmonary edema, atelectasis, or acute respiratory distress syndrome. VAEs are associated with adverse outcomes including prolonged mechanical ventilation, longer intensive care and hospital length-of-stay, and higher mortality rates. Studies to date suggest that minimizing sedation and optimizing fluid management can reduce VAE rates. SUMMARY: We review the CDC's recent updates on VAE surveillance definitions, methods, and tools, and provide an overview of the growing evidence base for VAE as a patient safety measure. Further work is needed to affirm and extend the current knowledge about how best to prevent VAEs.
PURPOSE OF REVIEW: The Centers for Disease Control and Prevention (CDC) recently transitioned from ventilator-associated pneumonia (VAP) surveillance to ventilator-associated event (VAE) surveillance in adult inpatient settings. Since the transition, several modifications have been made to improve surveillance methods, and there is a growing body of data regarding the epidemiology, risk factors, and preventability of VAEs. RECENT FINDINGS: The VAE surveillance definition algorithm is based on objective criteria and includes three tiers: ventilator-associated conditions, infection-related ventilator-associated complications, and possible and probable VAP. VAE surveillance expands the purview of surveillance beyond pneumonia alone to include additional complications of mechanical ventilation. Most VAEs are caused by pneumonia, pulmonary edema, atelectasis, or acute respiratory distress syndrome. VAEs are associated with adverse outcomes including prolonged mechanical ventilation, longer intensive care and hospital length-of-stay, and higher mortality rates. Studies to date suggest that minimizing sedation and optimizing fluid management can reduce VAE rates. SUMMARY: We review the CDC's recent updates on VAE surveillance definitions, methods, and tools, and provide an overview of the growing evidence base for VAE as a patient safety measure. Further work is needed to affirm and extend the current knowledge about how best to prevent VAEs.
Authors: Jennifer P Stevens; Bartlomiej Kachniarz; Sharon B Wright; Jean Gillis; Daniel Talmor; Peter Clardy; Michael D Howell Journal: Crit Care Med Date: 2014-03 Impact factor: 7.598
Authors: Peter M C Klein Klouwenberg; Maaike S M van Mourik; David S Y Ong; Janneke Horn; Marcus J Schultz; Olaf L Cremer; Marc J M Bonten Journal: Am J Respir Crit Care Med Date: 2014-04-15 Impact factor: 21.405
Authors: Juliana Barr; Gilles L Fraser; Kathleen Puntillo; E Wesley Ely; Céline Gélinas; Joseph F Dasta; Judy E Davidson; John W Devlin; John P Kress; Aaron M Joffe; Douglas B Coursin; Daniel L Herr; Avery Tung; Bryce R H Robinson; Dorrie K Fontaine; Michael A Ramsay; Richard R Riker; Curtis N Sessler; Brenda Pun; Yoanna Skrobik; Roman Jaeschke Journal: Crit Care Med Date: 2013-01 Impact factor: 7.598
Authors: Lucy Z Kornblith; Anamaria J Robles; Amanda S Conroy; Brittney J Redick; Benjamin M Howard; Carolyn M Hendrickson; Sara Moore; Mary F Nelson; Farzad Moazed; Rachael A Callcut; Carolyn S Calfee; Mitchell Jay Cohen Journal: J Trauma Acute Care Surg Date: 2019-08 Impact factor: 3.313
Authors: Meghan M Cirulis; Mitchell T Hamele; Chris R Stockmann; Tellen D Bennett; Susan L Bratton Journal: Pediatr Crit Care Med Date: 2016-02 Impact factor: 3.624
Authors: Shelley S Magill; Qunna Li; Cindy Gross; Margaret Dudeck; Katherine Allen-Bridson; Jonathan R Edwards Journal: Crit Care Med Date: 2016-12 Impact factor: 7.598
Authors: Douglas A Colquhoun; Ryan P Davis; Theodore T Tremper; Jenny J Mace; Jan M Gombert; William D Sheldon; Joseph J Connolly; Justin F Adams; Kevin K Tremper Journal: BMC Anesthesiol Date: 2021-07-24 Impact factor: 2.217