Literature DB >> 24944717

Medicines shortages-unpicking the evidence from a year in South Africa.

Andy Gray1.   

Abstract

Although medicines shortages are a persistent and challenging problem for all health systems, the reasons for such shortages vary considerably between settings. Understanding the range of problems encountered, and the specific reasons for each medicines shortage event, may help to identify the most appropriate systems-wide responses. South Africa's health system is, at this point, still clearly divided between a better-resourced private sector and an overwhelmed public sector. Medicines selection and procurement processes in the two sectors are markedly different. However, in both sectors there is a dearth of publicly accessible information about the incidence and consequences of medicines shortages. This brief report describes the medicines selection and procurement processes currently applied in South Africa's public health sector, and then describes the nature of the medicines shortages that have been experienced in the KwaZulu-Natal provincial health services between July 2012 and June 2013. The degree to which these shortages might have been managed differently, had the recommendations developed by the International Pharmaceutical Federation Summit on Medicines Shortages been implemented, is then explored.

Keywords:  Medicines shortages; South Africa; public sector selection and procurement; systems-wide responses

Year:  2014        PMID: 24944717      PMCID: PMC4051355          DOI: 10.4066/AMJ.2014.1932

Source DB:  PubMed          Journal:  Australas Med J        ISSN: 1836-1935


  10 in total

1.  Prescription drug shortages plague US.

Authors:  F Charatan
Journal:  BMJ       Date:  2001-01-20

2.  The shortage of essential chemotherapy drugs in the United States.

Authors:  Mandy L Gatesman; Thomas J Smith
Journal:  N Engl J Med       Date:  2011-10-31       Impact factor: 91.245

3.  Drug shortages--a critical challenge for the generic-drug market.

Authors:  Bruce A Chabner
Journal:  N Engl J Med       Date:  2011-10-31       Impact factor: 91.245

4.  Shortages of medicines: a complex global challenge.

Authors:  Andy Gray; Henri R Manasse
Journal:  Bull World Health Organ       Date:  2012-03-01       Impact factor: 9.408

5.  The reality of drug shortages--the case of the injectable agent propofol.

Authors:  Valerie Jensen; Bob A Rappaport
Journal:  N Engl J Med       Date:  2010-06-16       Impact factor: 91.245

6.  The drug shortage crisis.

Authors:  Jay M Mirtallo
Journal:  JPEN J Parenter Enteral Nutr       Date:  2011-07       Impact factor: 4.016

7.  Call to action: finding solutions for the drug shortage crisis in the United States.

Authors:  E R Fox; L S Tyler
Journal:  Clin Pharmacol Ther       Date:  2013-02       Impact factor: 6.875

8.  Economic and technological drivers of generic sterile injectable drug shortages.

Authors:  J Woodcock; M Wosinska
Journal:  Clin Pharmacol Ther       Date:  2012-11-07       Impact factor: 6.875

9.  Drug shortages in the United States: a critical evaluation of root causes and the need for action.

Authors:  D K Gupta; S-M Huang
Journal:  Clin Pharmacol Ther       Date:  2013-02       Impact factor: 6.875

10.  The global pediatric antiretroviral market: analyses of product availability and utilization reveal challenges for development of pediatric formulations and HIV/AIDS treatment in children.

Authors:  Brenda Waning; Ellen Diedrichsen; Elodie Jambert; Till Bärnighausen; Yun Li; Mieke Pouw; Suerie Moon
Journal:  BMC Pediatr       Date:  2010-10-17       Impact factor: 2.125

  10 in total
  4 in total

1.  Use of antibiotics in children younger than two years in eight countries: a prospective cohort study.

Authors:  Elizabeth T Rogawski; James A Platts-Mills; Jessica C Seidman; Sushil John; Mustafa Mahfuz; Manjeswori Ulak; Sanjaya K Shrestha; Sajid Bashir Soofi; Pablo Penataro Yori; Estomih Mduma; Erling Svensen; Tahmeed Ahmed; Aldo Am Lima; Zulfiqar A Bhutta; Margaret N Kosek; Dennis R Lang; Michael Gottlieb; Anita Km Zaidi; Gagandeep Kang; Pascal O Bessong; Eric R Houpt; Richard L Guerrant
Journal:  Bull World Health Organ       Date:  2016-11-03       Impact factor: 9.408

2.  Medicines shortages in Pakistan: a qualitative study to explore current situation, reasons and possible solutions to overcome the barriers.

Authors:  Muhammad Atif; Iram Malik; Irem Mushtaq; Saima Asghar
Journal:  BMJ Open       Date:  2019-09-04       Impact factor: 2.692

3.  Frequency of bystander exposure to antibiotics for enteropathogenic bacteria among young children in low-resource settings.

Authors:  Elizabeth T Rogawski McQuade; Stephanie A Brennhofer; Sarah E Elwood; Timothy L McMurry; Joseph A Lewnard; Estomih R Mduma; Sanjaya Shrestha; Najeeha Iqbal; Pascal O Bessong; Gagandeep Kang; Margaret Kosek; Aldo A M Lima; Tahmeed Ahmed; Jie Liu; Eric R Houpt; James A Platts-Mills
Journal:  Proc Natl Acad Sci U S A       Date:  2022-08-29       Impact factor: 12.779

Review 4.  Drug Shortage: Causes, Impact, and Mitigation Strategies.

Authors:  Sundus Shukar; Fatima Zahoor; Khezar Hayat; Amna Saeed; Ali Hassan Gillani; Sumaira Omer; Shuchen Hu; Zaheer-Ud-Din Babar; Yu Fang; Caijun Yang
Journal:  Front Pharmacol       Date:  2021-07-09       Impact factor: 5.810

  4 in total

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