Hideaki Suzuki1, Takahisa Tabata2, Hiroki Koizumi2, Nobusuke Hohchi2, Shoko Takeuchi2, Takuro Kitamura2, Yoshihisa Fujino3, Toyoaki Ohbuchi2. 1. Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan suzuhyde@med.uoeh-u.ac.jp. 2. Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan. 3. Department of Preventive Medicine and Community Health, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Abstract
OBJECTIVE: This study aimed to create a multiple regression model for predicting hearing outcomes of idiopathic sudden sensorineural hearing loss (ISSNHL). METHODS: The participants were 205 consecutive patients (205 ears) with ISSNHL (hearing level ≥ 40 dB, interval between onset and treatment ≤ 30 days). They received systemic steroid administration combined with intratympanic steroid injection. Data were examined by simple and multiple regression analyses. Three hearing indices (percentage hearing improvement, hearing gain, and posttreatment hearing level [HLpost]) and 7 prognostic factors (age, days from onset to treatment, initial hearing level, initial hearing level at low frequencies, initial hearing level at high frequencies, presence of vertigo, and contralateral hearing level) were included in the multiple regression analysis as dependent and explanatory variables, respectively. RESULTS: In the simple regression analysis, the percentage hearing improvement, hearing gain, and HLpost showed significant correlation with 2, 5, and 6 of the 7 prognostic factors, respectively. The multiple correlation coefficients were 0.396, 0.503, and 0.714 for the percentage hearing improvement, hearing gain, and HLpost, respectively. Predicted values of HLpost calculated by the multiple regression equation were reliable with 70% probability with a 40-dB-width prediction interval. CONCLUSION: Prediction of HLpost by the multiple regression model may be useful to estimate the hearing prognosis of ISSNHL.
OBJECTIVE: This study aimed to create a multiple regression model for predicting hearing outcomes of idiopathic sudden sensorineural hearing loss (ISSNHL). METHODS: The participants were 205 consecutive patients (205 ears) with ISSNHL (hearing level ≥ 40 dB, interval between onset and treatment ≤ 30 days). They received systemic steroid administration combined with intratympanic steroid injection. Data were examined by simple and multiple regression analyses. Three hearing indices (percentage hearing improvement, hearing gain, and posttreatment hearing level [HLpost]) and 7 prognostic factors (age, days from onset to treatment, initial hearing level, initial hearing level at low frequencies, initial hearing level at high frequencies, presence of vertigo, and contralateral hearing level) were included in the multiple regression analysis as dependent and explanatory variables, respectively. RESULTS: In the simple regression analysis, the percentage hearing improvement, hearing gain, and HLpost showed significant correlation with 2, 5, and 6 of the 7 prognostic factors, respectively. The multiple correlation coefficients were 0.396, 0.503, and 0.714 for the percentage hearing improvement, hearing gain, and HLpost, respectively. Predicted values of HLpost calculated by the multiple regression equation were reliable with 70% probability with a 40-dB-width prediction interval. CONCLUSION: Prediction of HLpost by the multiple regression model may be useful to estimate the hearing prognosis of ISSNHL.
Authors: Jared H Hara; Julia A Zhang; Krupa R Gandhi; Anna Flaherty; Wayne Barber; Marcia A Leung; Lawrence P Burgess Journal: Laryngoscope Investig Otolaryngol Date: 2018-03-25
Authors: Keon Vin Park; Kyoung Ho Oh; Yong Jun Jeong; Jihye Rhee; Mun Soo Han; Sung Won Han; June Choi Journal: Clin Exp Otorhinolaryngol Date: 2020-03-12 Impact factor: 3.372