Literature DB >> 24944261

Reporting standards for studies of diagnostic test accuracy in dementia: The STARDdem Initiative.

Anna H Noel-Storr1, Jenny M McCleery1, Edo Richard1, Craig W Ritchie1, Leon Flicker1, Sarah J Cullum1, Daniel Davis1, Terence J Quinn1, Chris Hyde1, Anne W S Rutjes1, Nadja Smailagic1, Sue Marcus1, Sandra Black1, Kaj Blennow1, Carol Brayne1, Mario Fiorivanti1, Julene K Johnson1, Sascha Köpke1, Lon S Schneider1, Andrew Simmons1, Niklas Mattsson1, Henrik Zetterberg1, Patrick M M Bossuyt1, Gordon Wilcock1, Rupert McShane2.   

Abstract

OBJECTIVE: To provide guidance on standards for reporting studies of diagnostic test accuracy for dementia disorders.
METHODS: An international consensus process on reporting standards in dementia and cognitive impairment (STARDdem) was established, focusing on studies presenting data from which sensitivity and specificity were reported or could be derived. A working group led the initiative through 4 rounds of consensus work, using a modified Delphi process and culminating in a face-to-face consensus meeting in October 2012. The aim of this process was to agree on how best to supplement the generic standards of the STARD statement to enhance their utility and encourage their use in dementia research.
RESULTS: More than 200 comments were received during the wider consultation rounds. The areas at most risk of inadequate reporting were identified and a set of dementia-specific recommendations to supplement the STARD guidance were developed, including better reporting of patient selection, the reference standard used, avoidance of circularity, and reporting of test-retest reliability.
CONCLUSION: STARDdem is an implementation of the STARD statement in which the original checklist is elaborated and supplemented with guidance pertinent to studies of cognitive disorders. Its adoption is expected to increase transparency, enable more effective evaluation of diagnostic tests in Alzheimer disease and dementia, contribute to greater adherence to methodologic standards, and advance the development of Alzheimer biomarkers.
© 2014 American Academy of Neurology.

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Year:  2014        PMID: 24944261      PMCID: PMC4115600          DOI: 10.1212/WNL.0000000000000621

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  32 in total

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