| Literature DB >> 24943911 |
Luigi Messori1, Tiziano Marzo, Antonello Merlino.
Abstract
The X-ray structure of the adduct formed between oxaliplatin and the model protein hen egg white lysozyme is reported here. The structure is compared with those of cisplatin and carboplatin derivatives, previously solved. Relevant changes are highlighted among these crystal structures that are suggestive of significant differences in the reactivity of platinum drugs with this protein; possible biological implications are discussed.Entities:
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Year: 2014 PMID： 24943911 DOI： 10.1039/c4cc02254h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222