Literature DB >> 2494346

Preliminary crystallographic data for NAD(P)H quinone reductase isolated from the Walker 256 rat carcinoma cell line.

J V Skelly1, D A Suter, R J Knox, E Garman, D I Stuart, M R Sanderson, J J Roberts, S Neidle.   

Abstract

An NAD(P)H quinone reductase isolated from Walker rat 256 carcinoma cells has been crystallized in a form suitable for high-resolution structural analysis. The crystals belong to orthorhombic space group P2(1)2(1)2(1) with cell parameters a = 168.15 A, b = 105.09 A and c = 67.38 A and contain four monomeric or two dimeric enzyme molecules per asymmetric unit. Diffraction extends beyond 2.3 A resolution.

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Year:  1989        PMID: 2494346     DOI: 10.1016/0022-2836(89)90233-7

Source DB:  PubMed          Journal:  J Mol Biol        ISSN: 0022-2836            Impact factor:   5.469


  2 in total

1.  A two-domain structure for the two subunits of NAD(P)H:quinone acceptor oxidoreductase.

Authors:  S Chen; P S Deng; J M Bailey; K M Swiderek
Journal:  Protein Sci       Date:  1994-01       Impact factor: 6.725

2.  The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction.

Authors:  R Li; M A Bianchet; P Talalay; L M Amzel
Journal:  Proc Natl Acad Sci U S A       Date:  1995-09-12       Impact factor: 11.205

  2 in total

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